Marsha Mason portrays Janice Templeton, a mother whose life is turned upside down when she meets Elliot Hoover and discovers a connection to her past.
Anthony Hopkins plays Elliot Hoover, a man who believes Janice's daughter is the reincarnation of his own deceased child.
John Beck takes on the role of Bill Templeton, Janice's husband who struggles to come to terms with the supernatural events surrounding their family.
Susan Swift plays Ivy Templeton, Janice and Bill's young daughter who becomes the center of a mysterious and haunting connection.
Norman Lloyd portrays Dr. Steven Lipscomb, a psychiatrist who becomes involved in the unusual case of Audrey Rose.
John Hillerman appears as Scott Velle, a supporting character caught up in the supernatural events surrounding Janice and Elliot.
Robert Walden takes on the role of Brice Mack, a character whose involvement adds layers to the unfolding mystery of Audrey Rose.
Philip Sterling plays Judge Langley, a figure who becomes entangled in the legal implications of the spiritual connection at the heart of Audrey Rose.
Ivy Jones portrays Mary Lou Sides, a character involved in the events surrounding Janice Templeton and her family.
Stephen Pearlman appears as Russ Rothman, a character whose presence adds to the tension and mystery of Audrey Rose.
Aly Wassil takes on the role of Maharishi Gupta Pradesh, a character whose spiritual beliefs intersect with the unfolding story of Audrey Rose.
Mary Jackson appears as Mother Veronica, a figure whose presence adds a layer of spiritual guidance to the events of Audrey Rose.
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