Alan Arkin plays Capt. John Yossarian, the protagonist of the movie who is a U.S. Army Air Forces bombardier trying to maintain his sanity while fulfilling his service requirements.
Martin Balsam portrays Col. Cathcart, a military officer obsessed with increasing the number of combat missions required for his subordinates to complete before they can be sent home.
Richard Benjamin takes on the role of Maj. Danby, an intelligence officer at the airbase who serves as a link between the soldiers and the higher-ups in the military hierarchy.
Art Garfunkel plays Capt. Nately, a young and idealistic officer who becomes infatuated with a local woman in the midst of the chaos and absurdity of war.
Jack Gilford portrays Dr. 'Doc' Daneeka, the squadron flight surgeon who constantly seeks ways to be declared insane in order to be relieved from duty.
Buck Henry takes on the role of Lt. Col. Korn, one of the antagonistic officers responsible for implementing the illogical and dangerous policies that affect the soldiers.
Bob Newhart embodies the character of Maj. Major Major, an officer who attempts to avoid interacting with others by scheduling appointments when he knows he won't be available.
Anthony Perkins plays Chaplain Capt. A.T. Tappman, the well-intentioned but often ineffective Protestant chaplain who tries to provide spiritual support to the soldiers amidst the chaos of war.
Paula Prentiss portrays Nurse Duckett, a compassionate and intelligent nurse who forms a close relationship with the disillusioned protagonist, Capt. Yossarian.
Martin Sheen takes on the role of 1st Lt. Dobbs, one of the young and inexperienced pilots who becomes entangled in the bureaucratic nightmares and moral dilemmas of war.
Jon Voight plays 1st Lt. Milo Minderbinder, a cunning and opportunistic officer who runs a black-market syndicate, exploiting the war for personal profit at the expense of his comrades.
Orson Welles portrays Brigadier General Dreedle, a high-ranking and authoritarian officer whose decisions and behavior further showcase the absurdity and cruelty of military bureaucracy.
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