Rick Moranis plays Wayne Szalinski, a scientist who accidentally enlarges his toddler son Adam.
Marcia Strassman portrays Diane Szalinski, Wayne's wife and mother of their children.
Robert Oliveri takes on the role of Nick Szalinski, the older son of the Szalinski family.
Daniel Shalikar plays Adam Szalinski, the toddler who accidentally becomes a giant.
Joshua Shalikar also portrays Adam Szalinski, alongside his twin brother Daniel.
Lloyd Bridges appears as Clifford Sterling, the head of the company conducting experiments on growth.
John Shea takes on the role of Hendrickson, who is involved in the scientific experiments.
Keri Russell plays Mandy, a babysitter hired to look after the Szalinski children.
Ron Canada portrays Marshall Brooks, a government official involved in dealing with the giant toddler.
Amy O'Neill reprises her role as Amy Szalinski, Nick's younger sister.
Michael Milhoan appears as Capt. Ed Myerson, a military officer trying to handle the giant toddler situation.
Gregory Sierra takes on the role of Terence Wheeler, a scientist involved in the growth experiment.
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