Jodie Foster portrays the title character Nell Kellty, a young woman who has grown up in isolation and speaks her unique language.
Liam Neeson plays Dr. Lovell, a psychologist who investigates and tries to understand Nell's circumstances and way of life.
In the role of Dr. Paula Olsen, Natasha Richardson is a caring doctor who strives to help Nell adapt to the outside world.
Richard Libertini portrays Dr. Paley, a compassionate individual who helps in Nell's journey of integration into society.
Robin Mullins plays Mary Peterson, a supportive individual who forms a bond with Nell during her interactions.
Nick Searcy takes on the role of Sheriff Todd Peterson, a local law enforcement officer who encounters Nell in the community.
Jeremy Davies portrays Billy Fisher, a character who interacts with Nell and plays a role in her experiences outside her isolated life.
O'Neal Compton appears as Don Fontana, the attorney representing Dr. Lovell in certain aspects of the story.
Joe Inscoe plays the role of Judge, a figure involved in legal proceedings related to Nell's situation.
Stephanie Dawn Wood portrays Ruthie Lovell, a character connected to Dr. Lovell and his personal life.
Heather M. Bomba appears as one of the Twins, part of the community where Nell's story unfolds.
Marianne E. Bomba takes on the role of the other Twin, adding depth to the setting and interactions in the film.
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