Ben Stiller plays Jerry Stahl, a successful TV writer whose life spirals out of control due to his drug addiction.
Elizabeth Hurley portrays Sandra, a woman who becomes involved with Jerry Stahl amidst his struggles with addiction.
Maria Bello takes on the role of Kitty, a supporting character in Jerry Stahl's life.
Owen Wilson plays Nicky, a friend of Jerry Stahl who is also caught up in the world of addiction.
Lourdes Benedicto embodies the character of Vola, adding depth to the story of Jerry Stahl's challenges.
Peter Greene is Gus, a character who interacts with Jerry Stahl during his difficult journey.
Cheryl Ladd appears as Pamela Verlaine, a figure in Jerry Stahl's life affected by his struggles.
Fred Willard portrays Craig Ziffer, a character who brings a unique perspective to the narrative.
Charles Fleischer takes on the role of Allen from Mr. Chompers, contributing to the unfolding story.
Janeane Garofalo is Jana Farmer, a character adding layers to the experiences of Jerry Stahl.
Connie Nielsen embodies the character Dagmar, bringing complexity to the narrative of Permanent Midnight.
Sandra Oh plays a Friend, a character who impacts Jerry Stahl's journey through addiction in the film.
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