Sally Field portrays Lilah Krytsick, an aspiring comedienne looking to break into the stand-up comedy world.
Tom Hanks plays Steven Gold, a seasoned stand-up comedian who takes Lilah under his wing.
John Goodman takes on the role of John Krytsick, Lilah's husband who struggles with her comedy aspirations.
Mark Rydell portrays Romeo, a veteran comedian and mentor to the younger comics.
Kim Greist plays Madeline Urie, a fellow comedian who competes with Lilah for stage time.
Paul Mazursky appears as Arnold, a club owner in the comedy scene.
Damon Wayans is Percy, a struggling comedian trying to make his mark.
Taylor Negron portrays Albert Emperato, a comedian in the competitive world of stand-up.
Pam Matteson plays Utica Blake, a comedy club manager dealing with the antics of the comedians.
George McGrath appears as Brian, the Singing Nun, adding a unique act to the comedy lineup.
Barry Neikrug takes on the role of Krug, another comedian trying to find success in the industry.
Ángel Salazar appears as Rico, bringing his comedic style to the stage alongside his fellow comedians.
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