Meryl Streep portrays Mary Fisher, a successful romance novelist who becomes the target of Ruth Patchett's revenge.
Roseanne Barr plays the lead role of Ruth Patchett, a scorned housewife who seeks revenge on her husband's lover.
Ed Begley Jr. takes on the role of Bob Patchett, Ruth's husband who leaves her for Mary Fisher.
Linda Hunt portrays Hooper, an accomplice of Ruth who helps her carry out her revenge plot.
Sylvia Miles plays Mrs. Fisher, Mary Fisher's mother who gets caught up in the chaos.
Elisebeth Peters portrays Nicolette Patchett, Ruth and Bob's daughter caught in the middle of their feud.
A Martinez takes on the role of Garcia, a character entangled in Ruth's scheme for revenge.
Maria Pitillo plays Olivia Honey, a young woman who becomes involved in the chaotic situation.
Doris Belack portrays Paula, a character who is affected by Ruth's actions.
Mary Louise Wilson plays Mrs. Trumper, a character who witnesses the unfolding drama.
Susan Willis takes on the role of Ute, a supporting character in the story.
Jack Gilpin portrays Larry, a character who gets caught up in the events surrounding Ruth's revenge.
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