Christopher Walken portrays Johnny Smith, the main character who gains psychic abilities after waking up from a coma.
Brooke Adams plays Sarah Bracknell, a nurse and love interest of Johnny Smith in the movie.
Tom Skerritt takes on the role of Sheriff Bannerman, a key figure in the story who works closely with Johnny Smith.
Herbert Lom portrays Dr. Sam Weizak, a supporting character who aids Johnny Smith in understanding his psychic abilities.
Anthony Zerbe plays Roger Stuart, another important character in the movie who becomes intertwined with Johnny Smith's journey.
Colleen Dewhurst takes on the role of Henrietta Dodd, a character who plays a significant part in Johnny Smith's life.
Martin Sheen portrays Greg Stillson, an ambitious politician whose path collides with Johnny Smith's psychic visions.
Nicholas Campbell plays Frank Dodd, a character with a dark past who becomes entangled in Johnny Smith's life.
Sean Sullivan portrays Herb Smith, a minor character in the movie who is part of Johnny Smith's family.
Jackie Burroughs plays Vera Smith, another minor character who is part of Johnny Smith's family.
Géza Kovács takes on the role of Sonny Elliman, a character who interacts with Johnny Smith during his journey.
Roberta Weiss portrays Alma Frechette, a character who plays a part in Johnny Smith's story in The Dead Zone.
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