Jodie Foster portrays Clarice M. Starling, a young FBI trainee who seeks the help of Dr. Hannibal Lecter to catch a serial killer.
Anthony Hopkins takes on the role of Dr. Hannibal Lecter, a brilliant but psychotic psychiatrist serving life behind bars for his gruesome crimes.
Scott Glenn plays Jack Crawford, the head of the FBI's Behavioral Science Unit and Clarice Starling's mentor.
Ted Levine embodies the chilling character of Jame 'Buffalo Bill' Gumb, a serial killer who skins his victims to create a 'woman suit'.
Anthony Heald brings to life Dr. Frederick Chilton, the smug and arrogant chief administrator of the Baltimore State Hospital for the Criminally Insane.
Brooke Smith portrays Catherine Martin, the abducted daughter of Senator Ruth Martin, who becomes Buffalo Bill's latest captive.
Diane Baker is Senator Ruth Martin, the powerful mother of Catherine Martin who is desperate to save her daughter from the clutches of a menacing killer.
Kasi Lemmons plays Ardelia Mapp, Clarice's friend and fellow FBI trainee who provides support and solidarity in the male-dominated field.
Frankie Faison takes on the role of Barney Matthews, the compassionate and trusted orderly at the Baltimore State Hospital who maintains a respectful relationship with Dr. Lecter.
Tracey Walter portrays Lamar, an entomologist who provides valuable insight to Clarice Starling in her pursuit of the killer.
Charles Napier plays Lt. Boyle, a member of the Memphis Police Department who assists in the investigation of Buffalo Bill.
Danny Darst is Sgt. Tate, a local sheriff's officer who aids in the search for Buffalo Bill and the abducted women.
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