Tom Arnold plays Stanley Stupid, the well-meaning but dim-witted patriarch of the Stupid family.
Jessica Lundy portrays Joan Stupid, Stanley's equally clueless wife who unwittingly gets involved in his misadventures.
Bug Hall takes on the role of Buster Stupid, the Stupid family's son who often finds himself caught up in his parents' ridiculous schemes.
Alex McKenna plays Petunia Stupid, the Stupid family's daughter who adds to the chaos with her own unique brand of silliness.
Mark Metcalf portrays Colonel Neidermeyer, a stern military officer who becomes entangled in the Stupid family's nonsensical adventures.
Matt Keeslar plays Lieutenant Neal, Neidermeyer's loyal subordinate who tries to make sense of the Stupid family's bizarre behavior.
Christopher Lee appears as Evil Sender, a mysterious antagonist who crosses paths with the Stupids.
Frankie Faison is The Lloyd, a character who encounters the Stupid family during their comical escapades.
Robert Wise portrays Stanley's Neighbor, a befuddled bystander who gets caught up in the Stupid family's shenanigans.
David Ferry appears as the Late-night show host, a TV personality who interacts with the Stupid family in a memorable way.
Norman Jewison plays the TV Director in a humorous cameo role within the zany world of The Stupids.
Jenny McCarthy-Wahlberg portrays the Glamorous Actress who adds to the chaos and hilarity surrounding the Stupid family.
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