Tom Hanks stars as Lawrence Whatley Bourne III, a spoiled Yale graduate who volunteers for the Peace Corps in Thailand.
John Candy plays Tom Tuttle, a mysterious American who has been living in the Thai village for years.
Rita Wilson portrays Beth Wexler, a Peace Corps worker in Thailand who becomes involved with Lawrence Whatley Bourne III.
Tim Thomerson appears as John Reynolds, another Peace Corps member stationed in Thailand.
Gedde Watanabe takes on the role of At Toon, a Thai villager who interacts with the Peace Corps volunteers.
George Plimpton portrays Lawrence Bourne Jr., the father of Lawrence Whatley Bourne III.
Ernest Harada plays Chung Mee, a Thai woman who becomes a romantic interest for one of the volunteers.
Allan Arbus appears as Albert Bardenaro, an American expatriate living in Thailand.
Xander Berkeley takes on the role of Kent Sutcliffe, one of the Peace Corps volunteers in Thailand.
Ji-Tu Cumbuka plays Cicero, a character in the Thai village where the Peace Corps volunteers are stationed.
Jacqueline Evans appears as Aunt Eunice, a relative of one of the Peace Corps volunteers.
Pamela Gual portrays Tammy the Stewardess, a character who interacts with the volunteers during their journey to Thailand.
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