Check It Out! with Dr. Steve Brule (TV) Cast
The cast of Check It Out! with Dr. Steve Brule. Updated on October 28, 2025.
John C. Reilly
Dr. Steve Brule · 24 eps
2,065
wiki views
#2,956 overall

John C. Reilly plays Dr. Steve Brule, an unusual and often confused doctor exploring everyday subjects.

Atsushi Watanabe
Sushi Chef · 1 ep
Jonny Bowden
Self · 1 ep

Jonny Bowden appears as himself, contributing his expertise on nutrition.

Rod Davis
· 1 ep
William Holt
· 1 ep
Jose G. Lopez
Janitor · 1 ep

Jose G. Lopez plays the Janitor, a character who interacts with Dr. Steve Brule in various episodes.

Julie O'Brien
· 1 ep
Gloria Sandoval
· 1 ep
Karon Stocking
· 1 ep
Joji Yokoe
· 1 ep
Don Davis
Self · 1 ep

Don Davis appears as himself, bringing his music knowledge to the show.

Maria Bamford
Cynthia Driscoll · 1 ep
656
wiki views
#8,142 overall

Maria Bamford plays Cynthia Driscoll, a character who often crosses paths with Dr. Brule.

Bruce Eason
· 1 ep
Ian Halstein
· 1 ep
Nickolay Maleko
· 1 ep
Melissa Manning
· 1 ep
Liz Valente
· 1 ep
Bob Baker
Self · 1 ep
Scotty Castillo
· 1 ep
Ursula Heinle
Self · 1 ep
Sandy Sanders
Self · 1 ep
Stephan D. Gill
Steve Davis · 1 ep
Ann J. Elkin
Dr. Davis · 1 ep
Elaine Ballace
· 1 ep
Charles Bone
· 1 ep
Susan Cottrell
· 1 ep
Edward Diggsby
· 1 ep
Manuel Fierro
· 1 ep
Hunter Fox
· 1 ep
Sandy Jeanphilippe
· 1 ep
Fermin Lagunas
· 1 ep
Kenny Lopez
· 1 ep
Mark Malan
· 1 ep
David Markey
· 1 ep
Charles Matula
· 1 ep
Dwayne Mosco
· 1 ep
Wora Rapp
· 1 ep
Jacinta Robert
· 1 ep
Herman Rogue
· 1 ep
Brent Sweet
· 1 ep
Irma Thorn
· 1 ep
Tiny Ron
God · 1 ep
143
wiki views
#17,922 overall
Brian Ventimiglia
· 1 ep
Charles Villano
· 1 ep
Scott Wisman
· 1 ep
Yasmin Yas
· 1 ep
Gary Lecroix
Self · 1 ep
Ronnie Rodriguez
Self · 1 ep
Dayna Allen
· 1 ep
Linda Eaton
· 1 ep
Charles Erickson
· 1 ep
Regan Forston
· 1 ep
Purita Wattanakulchotikarn
Self · 1 ep
Ronald Barker
Self · 1 ep
Paulette Hunnewell
· 1 ep
Anthony Nguyen
· 1 ep
2
wiki views
#36,083 overall
Mauricio Solis
Goon · 1 ep
Joe Zacharia
· 1 ep
David Falk
Self · 1 ep
212
wiki views
#15,268 overall
David Jurasevich
Self · 1 ep
Martin Faigin
· 1 ep
Jolie Mason
· 1 ep
Amy Porter
· 1 ep
Sean Roach
Self · 1 ep
Kelyan Ayachi
· 1 ep
Aykut Bayrak
Self · 1 ep
Rob Karlin
· 1 ep
Sherri Smith
Fertility clinic nurse · 1 ep
LeRoy Thompson
· 1 ep
Donna Rusch
Linda Barrelli · 1 ep
Amy Moorman
· 1 ep
Darcy Vernier
· 1 ep
Reuban Piranian
· 1 ep
Daniel M. Hooper
· 1 ep
Lydia Sims
· 1 ep
Diamond
· 1 ep
Oberon Zell
Self · 1 ep
36
wiki views
#26,761 overall
Michael O'Garro Jr.
· 1 ep
Kevin Lee
· 1 ep
344
wiki views
#12,062 overall
Darin Rossi
· 1 ep
Irving Orozco
Self · 1 ep
Cheryl A. Smith
Self · 1 ep
Rolando W. Wolovich
Self · 1 ep
Bryan Heard Jr.
· 1 ep
Laine Lasanta
· 1 ep
Rhoen Reddy
· 1 ep
Ryce Waker
· 1 ep
David N. Alexander
· 1 ep
Adora Dei
Doctor · 1 ep
Gwen Holloway
ER Doctor · 1 ep
Lindsay McGrail
ER Nurse · 1 ep
June Mock
Doctor · 1 ep
Ernest L. Moore
· 1 ep
Bob Raynor
Uncle Gary · 2 eps
Ron Don Volante
Self · 4 eps
Bobby Javinett
· 1 ep
Andy Mardrosian
· 1 ep
Frank Vargas
· 1 ep
Christine Dupree
Girl in Dream · 1 ep
Sophiah Koikas
Girl in Dream · 1 ep
Top Check It Out! with Dr. Steve Brule Cast Members
Based on daily Wikipedia pageviews. Updated October 28, 2025.
#1
John C. Reillyas Dr. Steve Brule
2,065 views→
#2
Maria Bamfordas Cynthia Driscoll
656 views→
#3
Kevin Lee
344 views→
#4
David Falkas Self
212 views→
#5
Tiny Ronas God
143 views→
#6
Fabian Alomaras Inmate
82 views→
#7
David Liebe Hartas Self
61 views→
#8
Nancy Munozas Dorris Pringle-Brule-Salahari
39 views→
#9
Oberon Zellas Self
36 views→
#10
Kenny Alexander
30 views→
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