Check It Out! with Dr. Steve Brule (TV) Cast Popularity
The cast of Check It Out! with Dr. Steve Brule including daily popularity data. Updated on June 3, 2025.
Sort cast by:
Default
Actor Popularity
A-Z
154 total actors
John C. Reilly
as Dr. Steve Brule (24 episodes)

John C. Reilly plays Dr. Steve Brule, an unusual and often confused doctor exploring everyday subjects.

#1
Most popular actor on Check It Out! with Dr. Steve Brule
2,133 Wikipedia views yesterday
Atsushi Watanabe
as Sushi Chef (1 episode)
Jonny Bowden
as Self (1 episode)

Jonny Bowden appears as himself, contributing his expertise on nutrition.

Rod Davis
as (1 episode)
William Holt
as (1 episode)
Jose G. Lopez
as Janitor (1 episode)

Jose G. Lopez plays the Janitor, a character who interacts with Dr. Steve Brule in various episodes.

Julie O'Brien
as (1 episode)
Gloria Sandoval
as (1 episode)
Karon Stocking
as (1 episode)
Joji Yokoe
as (1 episode)
Don Davis
as Self (1 episode)

Don Davis appears as himself, bringing his music knowledge to the show.

Maria Bamford
as Cynthia Driscoll (1 episode)

Maria Bamford plays Cynthia Driscoll, a character who often crosses paths with Dr. Brule.

#2
Most popular actor on Check It Out! with Dr. Steve Brule
720 Wikipedia views yesterday
Bruce Eason
as (1 episode)
Ian Halstein
as (1 episode)
Nickolay Maleko
as (1 episode)
Melissa Manning
as (1 episode)
Liz Valente
as (1 episode)
Bob Baker
as Self (1 episode)
Scotty Castillo
as (1 episode)
Ursula Heinle
as Self (1 episode)
Sandy Sanders
as Self (1 episode)
Stephan D. Gill
as Steve Davis (1 episode)
Ann J. Elkin
as Dr. Davis (1 episode)
Elaine Ballace
as (1 episode)
Charles Bone
as (1 episode)
Susan Cottrell
as (1 episode)
Edward Diggsby
as (1 episode)
Manuel Fierro
as (1 episode)
Hunter Fox
as (1 episode)
Sandy Jeanphilippe
as (1 episode)
Fermin Lagunas
as (1 episode)
Kenny Lopez
as (1 episode)
Mark Malan
as (1 episode)
David Markey
as (1 episode)
Charles Matula
as (1 episode)
Dwayne Mosco
as (1 episode)
Wora Rapp
as (1 episode)
Jacinta Robert
as (1 episode)
Herman Rogue
as (1 episode)
Brent Sweet
as (1 episode)
Irma Thorn
as (1 episode)
Tiny Ron
as God (1 episode)
#5
Most popular actor on Check It Out! with Dr. Steve Brule
137 Wikipedia views yesterday
Brian Ventimiglia
as (1 episode)
Charles Villano
as (1 episode)
Scott Wisman
as (1 episode)
Yasmin Yas
as (1 episode)
Gary Lecroix
as Self (1 episode)
Ronnie Rodriguez
as Self (1 episode)
Dayna Allen
as (1 episode)
Linda Eaton
as (1 episode)
Charles Erickson
as (1 episode)
Regan Forston
as (1 episode)
Purita Wattanakulchotikarn
as Self (1 episode)
Ronald Barker
as Self (1 episode)
Paulette Hunnewell
as (1 episode)
Anthony Nguyen
as (1 episode)
#13
Most popular actor on Check It Out! with Dr. Steve Brule
2 Wikipedia views yesterday
Mauricio Solis
as Goon (1 episode)
Joe Zacharia
as (1 episode)
David Falk
as Self (1 episode)
#4
Most popular actor on Check It Out! with Dr. Steve Brule
307 Wikipedia views yesterday
David Jurasevich
as Self (1 episode)
Martin Faigin
as (1 episode)
Jolie Mason
as (1 episode)
Amy Porter
as (1 episode)
Sean Roach
as Self (1 episode)
Kelyan Ayachi
as (1 episode)
Aykut Bayrak
as Self (1 episode)
Rob Karlin
as (1 episode)
Sherri Smith
as Fertility clinic nurse (1 episode)
LeRoy Thompson
as (1 episode)
Donna Rusch
as Linda Barrelli (1 episode)
Amy Moorman
as (1 episode)
Darcy Vernier
as (1 episode)
Reuban Piranian
as (1 episode)
Daniel M. Hooper
as (1 episode)
Lydia Sims
as (1 episode)
Diamond
as (1 episode)
Oberon Zell
as Self (1 episode)
#10
Most popular actor on Check It Out! with Dr. Steve Brule
24 Wikipedia views yesterday
Michael O'Garro Jr.
as (1 episode)
Kevin Lee
as (1 episode)
#3
Most popular actor on Check It Out! with Dr. Steve Brule
312 Wikipedia views yesterday
Darin Rossi
as (1 episode)
Irving Orozco
as Self (1 episode)
Cheryl A. Smith
as Self (1 episode)
Rolando W. Wolovich
as Self (1 episode)
Bryan Heard Jr.
as (1 episode)
Laine Lasanta
as (1 episode)
Rhoen Reddy
as (1 episode)
Ryce Waker
as (1 episode)
David N. Alexander
as (1 episode)
Adora Dei
as Doctor (1 episode)
Gwen Holloway
as ER Doctor (1 episode)
Lindsay McGrail
as ER Nurse (1 episode)
June Mock
as Doctor (1 episode)
Ernest L. Moore
as (1 episode)
Bob Raynor
as Uncle Gary (2 episodes)
Ron Don Volante
as Self (4 episodes)
Bobby Javinett
as (1 episode)
Andy Mardrosian
as (1 episode)
Frank Vargas
as (1 episode)
Christine Dupree
as Girl in Dream (1 episode)
Sophiah Koikas
as Girl in Dream (1 episode)
For the best insights and data about the TV show Check It Out! with Dr. Steve Brule, visit our main Check It Out! with Dr. Steve Brule page.