Bio-Dome Cast

Pauly Shore portrays Bud Macintosh, one of the two leads who accidentally get locked inside the Bio-Dome.

Stephen Baldwin plays Doyle Johnson, the other lead who joins Bud in the Bio-Dome escapade.

William Atherton stars as Dr. Noah Faulkner, the creator of the Bio-Dome experiment.

Joey Lauren Adams appears as Monique, a character in the Bio-Dome.

Teresa Hill portrays Jen, one of the researchers in the Bio-Dome project.

Henry Gibson plays William Leaky, the scientific advisor for the Bio-Dome project.

Kevin West stars as T.C. Romulus, a character part of the Bio-Dome experiment.

Denise Dowse appears as Olivia Biggs, a member of the Bio-Dome project team.

Dara Tomanovich portrays Mimi Simkins, another character involved in the Bio-Dome project.

Rose McGowan plays Denise, a character in the Bio-Dome who encounters the main leads.

Taylor Negron appears as Russell, a character connected to the Bio-Dome experiment.

Patricia Hearst plays Doyle's Mother in Bio-Dome, a cameo role in the film.