Despicable Me 4 Cast
The cast of Despicable Me 4 including popularity data. Data for May 16, 2025.
Steve Carell
as Gru (voice)

Voices both Gru and Dru, the main characters in the film.

#2
Most popular actor on Despicable Me 4
10,369 Wikipedia views yesterday
Kristen Wiig
as Lucy (voice)

Brings the character of Lucy Wilde to life with her voice acting.

#11
Most popular actor on Despicable Me 4
2,593 Wikipedia views yesterday
Will Ferrell
as Maxime (voice)
#7
Most popular actor on Despicable Me 4
3,731 Wikipedia views yesterday
Sofía Vergara
as Valentina (voice)
#4
Most popular actor on Despicable Me 4
7,872 Wikipedia views yesterday
Miranda Cosgrove
as Margo (voice)

Voices the character of Margo, adding depth to the film's protagonists.

#5
Most popular actor on Despicable Me 4
7,494 Wikipedia views yesterday
Dana Gaier
as Edith (voice)

Voices the character of Edith, adding her unique energy to the cast.

#21
Most popular actor on Despicable Me 4
76 Wikipedia views yesterday
Madison Polan
as Agnes (voice)
Pierre Coffin
as Minions (voice)

Lends his voice to the mischievous and lovable Minions.

Chris Renaud
as Principal Übelschlecht (voice)
Steve Coogan
as Silas (voice)

Brings humor and flair to the characters of Silas Ramsbottom and Fritz.

#14
Most popular actor on Despicable Me 4
1,890 Wikipedia views yesterday
Stephen Colbert
as Perry Prescott (voice)
#6
Most popular actor on Despicable Me 4
4,989 Wikipedia views yesterday
Chloe Fineman
as Patsy Prescott (voice)
#10
Most popular actor on Despicable Me 4
2,829 Wikipedia views yesterday
Jon Hamm
as
#1
Most popular actor on Despicable Me 4
10,720 Wikipedia views yesterday
Joey King
as Poppy Prescott (voice)
#8
Most popular actor on Despicable Me 4
3,223 Wikipedia views yesterday
Chris Renaud
as (voice)
Laraine Newman
as Melora / Additional Voices (voice)
#13
Most popular actor on Despicable Me 4
2,110 Wikipedia views yesterday
John DiMaggio
as Bus Driver (voice)
#16
Most popular actor on Despicable Me 4
1,269 Wikipedia views yesterday
Tara Strong
as Additional Voices (voice)
#15
Most popular actor on Despicable Me 4
1,851 Wikipedia views yesterday
Romesh Ranganathan
as Additional Voices (voice)
#17
Most popular actor on Despicable Me 4
861 Wikipedia views yesterday
Brad Ableson
as Additional Voices (voice)
Barbara Harris
as Additional Voices (voice)
Eden Boulton
as Additional Voices (voice)
JP Karliak
as Additional Voices (voice)
#23
Most popular actor on Despicable Me 4
12 Wikipedia views yesterday
Cathy Cavadini
as Additional Voices (voice)
#19
Most popular actor on Despicable Me 4
134 Wikipedia views yesterday
Arif S. Kinchen
as Additional Voices (voice)
Will Collyer
as Additional Voices (voice)
Jeremy Maxwell
as Additional Voices (voice)
Abby Craden
as Additional Voices (voice)
Ken Daurio
as Additional Voices (voice)
Khary Payton
as Additional Voices (voice)
#18
Most popular actor on Despicable Me 4
442 Wikipedia views yesterday
John DeMita
as Additional Voices (voice)
#22
Most popular actor on Despicable Me 4
42 Wikipedia views yesterday
Aaron Fors
as Additional Voices (voice)
Isaac Robinson-Smith
as Additional Voices (voice)
Willow Geer
as Additional Voices (voice)
#20
Most popular actor on Despicable Me 4
100 Wikipedia views yesterday
Isa Hall
as Additional Voices (voice)
Nisa Ward
as Additional Voices (voice)
Aaron Hendry
as Additional Voices (voice)
Andreana Weiner
as Additional Voices (voice)
Colette Whitaker
as Additional Voices (voice)
Jason Segel
as Vector (voice) (uncredited)
#9
Most popular actor on Despicable Me 4
2,924 Wikipedia views yesterday
Benjamin Bratt
as El Macho (voice) (uncredited)
#3
Most popular actor on Despicable Me 4
8,289 Wikipedia views yesterday
Trey Parker
as Balthazar Bratt (voice) (uncredited)
#12
Most popular actor on Despicable Me 4
2,129 Wikipedia views yesterday
For the best insights and data about Despicable Me 4, visit our main Despicable Me 4 page.