Despicable Me 4 Cast
The cast of Despicable Me 4 including popularity data. Data for March 26, 2025.
Steve Carell
as Gru (voice)

Voices both Gru and Dru, the main characters in the film.

#1
Most popular actor on Despicable Me 4
7,459 Wikipedia views yesterday
Kristen Wiig
as Lucy (voice)

Brings the character of Lucy Wilde to life with her voice acting.

#11
Most popular actor on Despicable Me 4
2,814 Wikipedia views yesterday
Will Ferrell
as Maxime (voice)
#5
Most popular actor on Despicable Me 4
3,847 Wikipedia views yesterday
Sofía Vergara
as Valentina (voice)
#4
Most popular actor on Despicable Me 4
4,659 Wikipedia views yesterday
Miranda Cosgrove
as Margo (voice)

Voices the character of Margo, adding depth to the film's protagonists.

#8
Most popular actor on Despicable Me 4
3,110 Wikipedia views yesterday
Dana Gaier
as Edith (voice)

Voices the character of Edith, adding her unique energy to the cast.

#21
Most popular actor on Despicable Me 4
94 Wikipedia views yesterday
Madison Polan
as Agnes (voice)
Pierre Coffin
as Minions (voice)

Lends his voice to the mischievous and lovable Minions.

Chris Renaud
as Principal Übelschlecht (voice)
Steve Coogan
as Silas (voice)

Brings humor and flair to the characters of Silas Ramsbottom and Fritz.

#14
Most popular actor on Despicable Me 4
2,463 Wikipedia views yesterday
Stephen Colbert
as Perry Prescott (voice)
#9
Most popular actor on Despicable Me 4
3,057 Wikipedia views yesterday
Chloe Fineman
as Patsy Prescott (voice)
#16
Most popular actor on Despicable Me 4
1,175 Wikipedia views yesterday
Jon Hamm
as
#2
Most popular actor on Despicable Me 4
5,277 Wikipedia views yesterday
Joey King
as Poppy Prescott (voice)
#3
Most popular actor on Despicable Me 4
4,898 Wikipedia views yesterday
Chris Renaud
as (voice)
Laraine Newman
as Melora / Additional Voices (voice)
#7
Most popular actor on Despicable Me 4
3,137 Wikipedia views yesterday
John DiMaggio
as Bus Driver (voice)
#15
Most popular actor on Despicable Me 4
1,546 Wikipedia views yesterday
Tara Strong
as Additional Voices (voice)
#12
Most popular actor on Despicable Me 4
2,574 Wikipedia views yesterday
Romesh Ranganathan
as Additional Voices (voice)
#17
Most popular actor on Despicable Me 4
1,072 Wikipedia views yesterday
Brad Ableson
as Additional Voices (voice)
Barbara Harris
as Additional Voices (voice)
Eden Boulton
as Additional Voices (voice)
JP Karliak
as Additional Voices (voice)
#23
Most popular actor on Despicable Me 4
11 Wikipedia views yesterday
Cathy Cavadini
as Additional Voices (voice)
#19
Most popular actor on Despicable Me 4
125 Wikipedia views yesterday
Arif S. Kinchen
as Additional Voices (voice)
Will Collyer
as Additional Voices (voice)
Jeremy Maxwell
as Additional Voices (voice)
Abby Craden
as Additional Voices (voice)
Ken Daurio
as Additional Voices (voice)
Khary Payton
as Additional Voices (voice)
#18
Most popular actor on Despicable Me 4
770 Wikipedia views yesterday
John DeMita
as Additional Voices (voice)
#22
Most popular actor on Despicable Me 4
77 Wikipedia views yesterday
Aaron Fors
as Additional Voices (voice)
Isaac Robinson-Smith
as Additional Voices (voice)
Willow Geer
as Additional Voices (voice)
#20
Most popular actor on Despicable Me 4
95 Wikipedia views yesterday
Isa Hall
as Additional Voices (voice)
Nisa Ward
as Additional Voices (voice)
Aaron Hendry
as Additional Voices (voice)
Andreana Weiner
as Additional Voices (voice)
Colette Whitaker
as Additional Voices (voice)
Jason Segel
as Vector (voice) (uncredited)
#6
Most popular actor on Despicable Me 4
3,373 Wikipedia views yesterday
Benjamin Bratt
as El Macho (voice) (uncredited)
#10
Most popular actor on Despicable Me 4
3,048 Wikipedia views yesterday
Trey Parker
as Balthazar Bratt (voice) (uncredited)
#13
Most popular actor on Despicable Me 4
2,514 Wikipedia views yesterday
For the best insights and data about Despicable Me 4, visit our main Despicable Me 4 page.