Dyan Cannon portrays Lorrie, one of the doctors' wives dealing with the challenges that come with her husband's profession.
Richard Crenna plays Pete Brennan, a character intertwined with the lives of the other doctors' wives in the story.
Gene Hackman takes on the role of Dave Randolph, bringing depth to the character's experiences as a doctor's spouse.
Carroll O'Connor portrays Joe Gray, offering a unique perspective as a husband to one of the doctors in the film.
Rachel Roberts embodies Della Randolph, adding layers to the portrayal of a doctor's wife in the movie.
Janice Rule plays Amy Brennan, contributing to the interconnected relationships within the group of doctors' spouses.
Diana Sands takes on the role of Helen Straughn, bringing her own interpretation to the character of a doctor's wife.
Cara Williams portrays Maggie Gray, adding complexity to the dynamics of the doctors' wives' social circle.
Richard Anderson plays D.A. Douglas, a character who is part of the unfolding story involving the doctors' spouses.
Ralph Bellamy embodies Jake Porter, bringing his own style to the portrayal of a supporting character in the movie.
John Colicos portrays Mort Dellman, adding depth to the cast of characters in Doctors' Wives.
George Gaynes takes on the role of Paul McGill, contributing to the ensemble cast of doctors' spouses in the film.
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