Dennis Quaid plays Alex Gardner, a psychic who enters people's dreams.
Max von Sydow portrays Doctor Paul Novotny, a researcher in dream technology.
Christopher Plummer takes on the role of Bob Blair, a government official with ulterior motives.
Eddie Albert plays The President, a character involved with the dream experiments.
Kate Capshaw acts as Jane DeVries, a fellow researcher and love interest.
David Patrick Kelly portrays Tommy Ray Glatman, a dream assassin.
George Wendt plays Charlie Prince, a character connected to the dream project.
Larry Gelman plays Mr. Webber, a supporting character involved in the plot.
Cory 'Bumper' Yothers portrays Buddy, a character in the dream sequences.
Redmond Gleeson plays Snead, a character associated with the project.
Peter Jason takes on the role of Babcock, a supporting character in the film.
Chris Mulkey portrays Finch, adding to the cast of characters in the film.
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