Clint Eastwood plays the role of Philo Beddoe, a trucker and bare-knuckle brawler who travels with his pet orangutan, Clyde.
Sondra Locke portrays Lynn Halsey-Taylor, a country singer and love interest of Philo Beddoe.
Geoffrey Lewis takes on the role of Orville Boggs, Philo's best friend and traveling companion.
Manis provides the voice and movements for Clyde, Philo Beddoe's orangutan companion.
Beverly D'Angelo plays Echo, a waitress and romantic interest of Philo Beddoe.
Walter Barnes portrays Tank Murdock, a tough fighter and rival to Philo Beddoe.
George Chandler appears as the Clerk at D.M.V. who encounters Philo Beddoe in a memorable scene.
Roy Jenson takes on the role of Woody, a member of a motorcycle gang encountered by Philo Beddoe.
James McEachin plays Herb, a friend of Philo Beddoe who offers support throughout the film.
Bill McKinney appears as Dallas, Treasurer Biker, a member of a motorcycle gang encountered by Philo Beddoe.
William O'Connell portrays Elmo, Sergeant-At-Arms Biker, a member of a motorcycle gang in the film.
John Quade takes on the role of Cholla, The Biker Leader, the menacing leader of a motorcycle gang that clashes with Philo Beddoe.
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