Woody Allen plays Mickey Sachs, a nervous and hypochondriac television writer who is struggling with his career and love life.
Michael Caine portrays Elliot, a successful financial advisor who is married to Hannah but begins an affair with Lee, her sister.
Mia Farrow takes on the role of Hannah, a caring and organized woman who is married to Elliot but faces challenges in her personal life.
Carrie Fisher plays April Knox, a struggling actress who is in a tumultuous relationship with Hannah's ex-husband Mickey.
Barbara Hershey portrays Lee, a free-spirited and artistic woman who is romantically involved with Elliot, her sister Hannah's husband.
Lloyd Nolan plays Evan, Hannah's ex-husband and a successful venture capitalist who still holds a place in the family's dynamics.
Maureen O'Sullivan portrays Norma, the mother of Hannah, Lee, and Holly, who is a stabilizing presence in the family.
Daniel Stern plays Dusty, Hannah's neurotic and insecure partner who struggles with his self-esteem and relationships.
Max von Sydow portrays Frederick, a talented and mysterious artist who becomes romantically involved with Lee.
Dianne Wiest plays Holly, a struggling actress who is also the youngest sister, trying to find her path in life and love.
Lewis Black portrays Paul, a friend of Hannah and Elliot who often provides comedic relief with his sarcastic and witty remarks.
Julia Louis-Dreyfus briefly appears as Mary, a guest at a Thanksgiving dinner, adding a comedic touch to the ensemble cast.
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