Holly Hunter plays Claudia Larson, a single mother navigating through a complicated Thanksgiving reunion with her quirky family.
Robert Downey Jr. portrays Tommy Larson, Claudia's eccentric, trouble-making brother, who adds an extra layer of chaos to the family gathering.
Anne Bancroft plays Adele Larson, Claudia and Tommy's strong-willed mother, whose presence adds tension to the family gathering.
Charles Durning portrays Henry Larson, Claudia and Tommy's father, whose humorous and laid-back personality brings some levity to the family dynamics.
Dylan McDermott plays Leo Fish, Claudia's love interest, adding a romantic element to the hectic Thanksgiving celebrations.
Geraldine Chaplin portrays Aunt Glady, a quirky and eccentric member of the family who adds her own unique flair to the Thanksgiving gathering.
Steve Guttenberg plays Walter Wedman, Claudia's boyfriend, who tries to navigate through the chaotic interactions within her family.
Cynthia Stevenson portrays Joanne Larson Wedman, Claudia's sister, who adds her own family dynamic to the Thanksgiving reunion.
Claire Danes plays Kitt Larson, Claudia's teenage daughter, who navigates her own coming-of-age struggles amidst the family gathering.
Emily Ann Lloyd portrays Brittany Lace, Kitt's friend, who gets caught up in the chaotic Thanksgiving events alongside the Larson family.
Zack Duhame plays Walter Wedman Jr., Claudia's son, who adds his youthful energy to the mix of family dynamics during Thanksgiving.
Austin Pendleton portrays Peter Arnold, a family friend, whose presence at the Thanksgiving gathering adds another layer of complexity to the interactions.
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