Lili Taylor portrays Valerie Jean Solanas, a radical feminist writer who gained notoriety for her attempted assassination of Andy Warhol.
Jared Harris takes on the role of Andy Warhol, the iconic pop artist who was shot by Valerie Solanas.
Martha Plimpton plays Stevie, a close friend of Valerie Solanas who supports her radical beliefs and actions.
Lothaire Bluteau portrays Maurice Girodias, a publisher who crosses paths with Valerie Solanas.
Anna Thomson appears as Iris, a character connected to the world of Andy Warhol and Valerie Solanas.
Peter Friedman plays Alan Burke, a figure involved in the arts scene that intersects with Valerie Solanas.
Tahnee Welch embodies the character Viva, who was part of Andy Warhol's entourage during the 1960s.
Jamie Harrold portrays Jackie Curtis, a persona from the art and drag scene of that era.
Donovan Leitch takes on the role of Gerard Malanga, a poet and photographer associated with Andy Warhol's Factory.
Michael Imperioli appears as Ondine, a key figure in the avant-garde art and film world during the 1960s.
Reg Rogers embodies Paul Morrissey, a filmmaker who collaborated with Andy Warhol on multiple projects.
Bill Sage plays Tom Baker, a character linked to the events surrounding Valerie Solanas and Andy Warhol.
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