Kirstie Alley plays Mollie Jensen, a single mother who begins dating and falls in love with James while raising her son Mikey.
John Travolta portrays James Ubriacco, a cab driver who becomes romantically involved with Mollie and steps in as a father figure for Mikey.
Bruce Willis provides the voice for Mikey, Mollie's infant son who has hilarious insights as he navigates the world from his perspective.
Olympia Dukakis plays Rosie, Mollie's best friend and confidante who provides support and advice as Mollie balances motherhood and a romantic relationship.
George Segal portrays Albert, Mollie's wealthy and married lover who struggles with committing to a full-time relationship with her.
Abe Vigoda appears as Grandpa, Mikey's wise and loving grandfather who is a source of comfort and stability in the family.
Jacob Haines plays Mikey at age 1, showcasing the adorable and mischievous toddler phase of Mollie's son.
Jaryd Waterhouse portrays Mikey as a newborn, capturing the innocence and wonder of Mollie's infant son.
Joy Boushel appears as Melissa, a nurse who competes with Mollie for the affection of James and presents a challenge to their budding relationship.
Douglas Tuck plays the Cab Stealer, a character who adds a comedic element to the film as he gets involved in a humorous altercation with James.
Don S. Davis portrays Dr. Fleischer, a doctor who provides medical care for Mikey and offers guidance to Mollie on parenting issues.
William B. Davis appears as the Drug Doctor, a physician who treats Mollie and offers a humorous twist to a medical emergency in the film.
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