Slither Cast
The cast of Slither including popularity data. Data for June 04, 2025.
Nathan Fillion
as Bill Pardy

Portrays the character Bill Pardy.

#2
Most popular actor on Slither
7,700 Wikipedia views yesterday
Elizabeth Banks
as Starla Grant

Plays the role of Starla Grant.

#1
Most popular actor on Slither
17,609 Wikipedia views yesterday
Michael Rooker
as Grant Grant

Takes on the role of Grant Grant.

#6
Most popular actor on Slither
2,104 Wikipedia views yesterday
Gregg Henry
as Jack MacReady

Brings the character Jack MacReady to the screen.

#10
Most popular actor on Slither
479 Wikipedia views yesterday
Tania Saulnier
as Kylie Strutemyer

Portrays the character Kylie Strutemyer.

#15
Most popular actor on Slither
46 Wikipedia views yesterday
Don Thompson
as Wally

Plays the character Wally.

Jenna Fischer
as Shelby

Takes on the role of Shelby.

#4
Most popular actor on Slither
3,008 Wikipedia views yesterday
Xantha Radley
as Uptight Mom

Appears as Uptight Mom.

Dustin Milligan
as Drawing Boy
#8
Most popular actor on Slither
896 Wikipedia views yesterday
James Gunn
as Hank (uncredited)
#3
Most popular actor on Slither
3,892 Wikipedia views yesterday
Lloyd Kaufman
as Sad Drunk
Rob Zombie
as Dr. Karl (voice)
#5
Most popular actor on Slither
2,271 Wikipedia views yesterday
Haig Sutherland
as Trevor
Zak Ludwig
as Gina Kid
Iris Quinn
as Mrs. Strutemyer
William MacDonald
as Mr. Strutemyer
Matreya Fedor
as Emily Strutemyer
#14
Most popular actor on Slither
55 Wikipedia views yesterday
Amber Lee Bartlett
as Jenna Strutemyer
Brenda James
as Brenda Gutierrez
Tom Heaton
as Tourneur
#9
Most popular actor on Slither
552 Wikipedia views yesterday
Mary Black
as Woman in Basement
#12
Most popular actor on Slither
131 Wikipedia views yesterday
Ben Cotton
as Charlie
#13
Most popular actor on Slither
116 Wikipedia views yesterday
Lorena Gale
as Janene
#16
Most popular actor on Slither
45 Wikipedia views yesterday
Dee Jay Jackson
as Dwight
Nicholas Podbrey
as Diseased Grant part 1
Malcolm Scott
as Dude Joining Grant
Darren Shahlavi
as Brenda's Husband
#7
Most popular actor on Slither
988 Wikipedia views yesterday
Magda Apanowicz
as Friend (uncredited)
#11
Most popular actor on Slither
147 Wikipedia views yesterday
Kathryn Kirkpatrick
as Karaoke Woman
#17
Most popular actor on Slither
2 Wikipedia views yesterday
Corb Lund
as Lead Singer
Michael Cromien
as Fitzgibbon
Robert Musnicki
as Diseased Leader
Stephen Park
as Gleeked on Guy
#18
Most popular actor on Slither
2 Wikipedia views yesterday
Nicholas Podbrey
as Diseased Grant #1
Jeny Cassady
as Diseased Grant #2
Alette Falle
as Diseased Grant #3
Matt McInnis
as Head-Shot Norman
Rick Morwick
as Truck Driver (uncredited)
Mark Torgl
as Melvin Junko (Archive footage)
For the best insights and data about Slither, visit our main Slither page.