Slither Cast
The cast of Slither including popularity data. Data for April 02, 2025.
Nathan Fillion
as Bill Pardy

Portrays the character Bill Pardy.

#1
Most popular actor on Slither
7,464 Wikipedia views yesterday
Elizabeth Banks
as Starla Grant

Plays the role of Starla Grant.

#2
Most popular actor on Slither
3,554 Wikipedia views yesterday
Michael Rooker
as Grant Grant

Takes on the role of Grant Grant.

#6
Most popular actor on Slither
1,616 Wikipedia views yesterday
Gregg Henry
as Jack MacReady

Brings the character Jack MacReady to the screen.

#8
Most popular actor on Slither
532 Wikipedia views yesterday
Tania Saulnier
as Kylie Strutemyer

Portrays the character Kylie Strutemyer.

#14
Most popular actor on Slither
120 Wikipedia views yesterday
Don Thompson
as Wally

Plays the character Wally.

Jenna Fischer
as Shelby

Takes on the role of Shelby.

#4
Most popular actor on Slither
2,759 Wikipedia views yesterday
Xantha Radley
as Uptight Mom

Appears as Uptight Mom.

Dustin Milligan
as Drawing Boy
#7
Most popular actor on Slither
1,599 Wikipedia views yesterday
James Gunn
as Hank (uncredited)
#3
Most popular actor on Slither
3,500 Wikipedia views yesterday
Lloyd Kaufman
as Sad Drunk
Rob Zombie
as Dr. Karl (voice)
#5
Most popular actor on Slither
2,162 Wikipedia views yesterday
Haig Sutherland
as Trevor
Zak Ludwig
as Gina Kid
Iris Quinn
as Mrs. Strutemyer
William MacDonald
as Mr. Strutemyer
Matreya Fedor
as Emily Strutemyer
#16
Most popular actor on Slither
29 Wikipedia views yesterday
Amber Lee Bartlett
as Jenna Strutemyer
Brenda James
as Brenda Gutierrez
Tom Heaton
as Tourneur
#9
Most popular actor on Slither
316 Wikipedia views yesterday
Mary Black
as Woman in Basement
#11
Most popular actor on Slither
134 Wikipedia views yesterday
Ben Cotton
as Charlie
#10
Most popular actor on Slither
155 Wikipedia views yesterday
Lorena Gale
as Janene
#15
Most popular actor on Slither
44 Wikipedia views yesterday
Dee Jay Jackson
as Dwight
Nicholas Podbrey
as Diseased Grant part 1
Malcolm Scott
as Dude Joining Grant
Darren Shahlavi
as Brenda's Husband
#13
Most popular actor on Slither
122 Wikipedia views yesterday
Magda Apanowicz
as Friend (uncredited)
#12
Most popular actor on Slither
126 Wikipedia views yesterday
Kathryn Kirkpatrick
as Karaoke Woman
#17
Most popular actor on Slither
2 Wikipedia views yesterday
Corb Lund
as Lead Singer
Michael Cromien
as Fitzgibbon
Robert Musnicki
as Diseased Leader
Stephen Park
as Gleeked on Guy
#18
Most popular actor on Slither
1 Wikipedia views yesterday
Nicholas Podbrey
as Diseased Grant #1
Jeny Cassady
as Diseased Grant #2
Alette Falle
as Diseased Grant #3
Matt McInnis
as Head-Shot Norman
Rick Morwick
as Truck Driver (uncredited)
Mark Torgl
as Melvin Junko (Archive footage)
For the best insights and data about Slither, visit our main Slither page.