Penelope Ann Miller plays Dr. Margo Green, a dedicated evolutionary biologist who works at the Chicago Museum of Natural History.
Tom Sizemore portrays Lt. Vincent D'Agosta, a no-nonsense and determined police officer investigating a series of gruesome murders in the city.
Linda Hunt takes on the role of Dr. Ann Cuthbert, a knowledgeable and resourceful scientist assisting in deciphering the mysterious events at the museum.
James Whitmore plays Dr. Albert Frock, an experienced archaeologist with a deep understanding of ancient artifacts and their significance.
Clayton Rohner is Det. Hollingsworth, a skilled detective working alongside Lt. D'Agosta to unravel the terrifying truth behind the murders.
Chi Muoi Lo portrays Dr. Greg Lee, a talented researcher collaborating with Dr. Green to uncover the scientific explanation behind the malevolent force at play.
Thomas Ryan takes on the role of Tom Parkinson, a concerned museum curator caught up in the deadly events unfolding within the museum.
Robert Lesser portrays Mayor Robert Owen, the city's leader facing mounting pressure as the menacing creature causes chaos and fear among the citizens.
Diane Robin plays The Mayor's Wife, a supportive and resilient partner to Mayor Owen during the crisis gripping the city.
Lewis van Bergen portrays John Whitney, a member of the museum's board caught in the middle of the unfolding horror and escalating danger.
Constance Towers is Mrs. Harriet Blaisedale, a prominent figure in the city whose involvement in the events sheds light on the dark secrets hidden within.
Francis X. McCarthy plays Mr. George Blaisedale, a wealthy and influential individual whose connections to the museum reveal shocking truths about the unfolding terror.
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