Gail Matthius provides the voice for Shirley the Loon and Sissy Boo in the movie.
Tress MacNeille lends her voice to characters including Babs Bunny, Big Boo, Babs' Mother, Emily Duff, and others like Roseanne Barr and Barbara Walters.
Don Messick voices Hamton J. Pig and the Radio Announcer.
Paul Julian's archive sound is used for Road Runner in the movie.
Cree Summer voices Elmyra Duff, Mary Melody, and Oprah Winfrey in the film.
Joe Alaskey portrays Plucky Duck, Tupelo Toad, Johnny Carson, and voices characters like Elmer Fudd.
Maurice LaMarche provides the voices for Dizzy Devil, David Letterman, Horatio, and others, including Theatre Voice.
Jonathan Winters voices Wade Pig and Superman in the movie.
Charlie Adler voices Buster Bunny and the Usher in the film.
Edie McClurg lends her voice to Winnie Pig in the movie.
Frank Welker portrays Uncle Stinky Pig, Byron Basset, Furrball, Little Beeper, Gogo Dodo, Vinnie, Mac Duff, and additional characters.
Sorrell Booke provides the voice for Big Daddy Boo in the movie.
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