Paul Reubens plays Pee-wee Herman, the quirky and energetic main character who finds himself in a circus adventure.
Penelope Ann Miller portrays Winnie, Pee-wee's love interest who captivates him with her charm and grace.
Kris Kristofferson takes on the role of Mace Montana, a wise and seasoned circus performer who guides Pee-wee through his journey.
Valeria Golino plays Gina Piccolapupula, a vibrant and lively circus member who adds to the colorful atmosphere of the big top.
Benicio del Toro embodies Duke the Dog-Faced Boy, a unique and intriguing character with a special role in the circus.
Wayne White voices Vance the Pig, adding a touch of whimsy and humor to the cast of animated characters in the movie.
Susan Tyrrell portrays Midge Montana, a quirky and lovable member of the circus troupe who brings her own brand of charm to the story.
Albert Henderson appears as Mr. Ryan, a supporting character who plays a role in the unfolding events within the circus.
Jack Murdock plays Otis, a member of the circus ensemble who adds a sense of camaraderie and fun to the group dynamic.
David Byrd takes on the role of Deke, another member of the circus crew who contributes to the lively and colorful circus world.
Mary Jackson portrays Mrs. Dill, a character who adds depth and warmth to the community within the circus setting.
Frances Bay appears as Mrs. Haynes, another supporting character who enriches the narrative with her presence within the circus environment.
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