Cheech plays Cheech, one half of the iconic comedy duo along with Chong, known for their stoner humor and antics.
Tommy Chong portrays Chong, the other half of the legendary comedy duo Cheech & Chong, bringing his laid-back persona to the screen.
Evelyn Guerrero plays Donna, a character caught up in the zany adventures of Cheech and Chong.
Betty Kennedy portrays Candy, adding to the colorful cast of characters in the film.
Paul Reubens takes on the role of Pee-Wee Herman / Desk Clerk, showcasing his comedic talents in a memorable cameo.
Phil Hartman appears as Chick Hazard, adding his comedic chops to the mix.
Rita Wilson plays Actress / Hostage, contributing to the humorous chaos of the film.
Shelby Chong portrays the character Beautiful, adding to the eccentric and entertaining world of the movie.
Michael Winslow stars as Welfare Comedian, showcasing his unique sound effects and comedic talents.
Scott Thompson appears in a role that adds to the quirky and amusing ensemble of characters in the film.
Jay Moreno plays Kid, a character who becomes entangled in the wild escapades of Cheech and Chong.
Len Lawson appears as Businessman, contributing to the colorful cast of characters in the movie.
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