Johnny Depp plays Wade 'Cry-Baby' Walker, the charismatic leader of a group of delinquent youths known as the Drapes.
Amy Locane portrays Allison Vernon-Williams, a good girl who falls for Cry-Baby and gets pulled into his world of rebels and outsiders.
Susan Tyrrell takes on the role of Ramona Rickettes, Cry-Baby's eccentric and sharp-witted grandmother.
Iggy Pop appears as Belvedere Rickettes, Ramona's son and Cry-Baby's uncle, who shares his family's rebellious spirit.
Ricki Lake plays Pepper Walker, Cry-Baby's tough and loyal sister who stands by his side through thick and thin.
Traci Lords embodies the character of Wanda Woodward, a member of the Drapes known for her edgy style and fierce attitude.
Stephen Mailer portrays Baldwin, Allison's uptight boyfriend from the respectable side of town who clashes with Cry-Baby.
Darren E. Burrows plays Milton Hackett, one of Cry-Baby's loyal Drape friends, who adds humor and heart to the group.
Kim McGuire brings Mona 'Hatchet-Face' Malnorowski to life, a fierce and unconventional Drape member with a unique sense of style.
Polly Bergen appears as Mrs. Vernon-Williams, Allison's conservative and protective mother who disapproves of her daughter's association with Cry-Baby.
Patricia Hearst portrays Wanda's Mother, adding a touch of parental authority to the film's rebellious atmosphere.
David Nelson plays Wanda's Father, a character who represents the more conventional and traditional values in the story.
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