Johnny Depp plays the titular character, Don Juan DeMarco, a young man who thinks he is the famous lover from legend.
Marlon Brando portrays Dr. Jack Mickler, a psychiatrist who tries to understand and help Don Juan DeMarco.
Faye Dunaway appears as Marilyn Mickler, the wife of Dr. Jack Mickler and a supportive figure in his life.
Géraldine Pailhas plays Dona Ana, a character who interacts with Don Juan DeMarco and affects his journey.
Bob Dishy portrays Dr. Paul Showalter, a colleague of Dr. Jack Mickler who is involved in treating Don Juan DeMarco.
Rachel Ticotin appears as Doña Inez, a supportive and understanding character in Don Juan DeMarco's life.
Talisa Soto plays Doña Julia, a character connected to Don Juan DeMarco with a significant impact on his story.
Stephen Singer portrays Dr. Bill Dunsmore, a character involved in the psychiatric evaluation of Don Juan DeMarco.
Jo Champa appears as Sultana Gulbeyaz, adding depth to the storyline of Don Juan DeMarco.
Marita Geraghty plays the Woman in Restaurant, a minor character who interacts with the main cast in a significant moment.
Richard C. Sarafian portrays Detective Sy Tobias, a character involved in unraveling part of Don Juan DeMarco's story.
Tresa Hughes appears as Grandmother DeMarco, a character who likely has a pivotal role in Don Juan DeMarco's life story.
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