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Life As We Know It

Life As We Know It Cast

47 cast members · 24 with popularity data
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Most Popular Life As We Know It Cast Members

Melissa McCarthy is currently the most popular Life As We Know It cast member online with a Attention Score of 5.8. 1 of 47 cast members rank in the top 1,000 actors online today. Updated August 26, 2026.

1
Melissa McCarthy
DeeDee
5.8
#529 overall
2
Josh Duhamel
Eric Messer
3.7
#1,214 overall
3
Jean Smart
Helen Berenson (uncredited)
3.4
#1,342 overall
4
Katherine Heigl
Holly Berenson
3.2
#1,477 overall
5
Kumail Nanjiani
Simon
2.7
#1,921 overall
6
Christina Hendricks
Alison Novack
2.2
#2,537 overall
7
Josh Lucas
Sam
1.6
#3,656 overall
8
Hayes MacArthur
Peter Novak
1.6
#3,772 overall
9
Will Sasso
Josh
1.0
#6,171 overall
10
Rob Huebel
Ted
0.6
#9,408 overall
11
Andy Buckley
George Dunn
0.5
#10,672 overall
12
Andy Daly
Scott
0.5
#11,919 overall
13
Reggie Lee
Alan Burke
0.4
#13,258 overall
14
Majandra Delfino
Jenna
0.2
#18,169 overall
15
Jessica St. Clair
Beth
0.2
#19,026 overall
16
DeRay Davis
Lonnie
0.2
#19,628 overall
17
Bill Brochtrup
Gary
0.1
#23,730 overall
18
Melissa Ponzio
Victoria (Stripper Cousin)
0.1
#24,113 overall
19
Sarah Burns
Janine Groff
0.1
#24,584 overall
20
Wilbur Fitzgerald
Peter's Dad
0.1
#33,034 overall
21
Tara Ochs
Cousin's Wife
0.1
#34,674 overall
22
Markus Flanagan
Chef Phillipe
0.0
#39,064 overall
23
Eddie Frierson
Sports Announcer (voice)
0.0
#40,354 overall
24
Rob Nagle
Neighbor Dad
0.0
#49,453 overall
25
Alexis Clagett
Sophie
—
26
Brynn Clagett
Sophie
—
27
Brooke Clagett
Sophie
—
28
Brooke Liddell
Older Sophie
—
29
Kiley Liddell
Older Sophie
—
30
Britt Flatmo
Amy
—
31
Kate Kneeland
Female Patron
—
32
Jason MacDonald
Cousin
—
33
Brooke Josephson
Liz
—
34
Chan Ta Rivers
CPS Worker
—
35
Eric Phillips
Stoned Teenager
—
36
L. Warren Young
Officer Young
—
37
Johanna Jowett
Jill
—
38
Jody Thompson
Worker
—
39
Horace Toney
Court Clerk
—
40
Millie Fairchild
Older Woman
—
41
Katie Kneeland
Female Patron
—
42
Patricia French
Judge Gorling
—
43
Ron Clinton Smith
Contractor
—
44
Antwan Mills
Airport Security
—
45
Steve Nash
Self
—
46
Shayne Kohout
Pregnant Woman with DeeDee
—
47
Danielle L. Grant
Ticket Counter Lady
—
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