Diane Lane plays Adrienne, a woman escaping her life's complexities at an inn in Rodanthe where she meets Paul.
Richard Gere takes on the role of Paul, a doctor who comes to Rodanthe to confront his past and finds a connection with Adrienne.
Christopher Meloni portrays Jack, Adrienne's estranged husband seeking to reconcile their relationship.
Viola Davis appears as Jean, the friend and confidante of Adrienne who runs the inn in Rodanthe.
Becky Ann Baker plays Dot, a resident of Rodanthe and one of the characters surrounding the inn.
Scott Glenn portrays Robert Torrelson, a resident of Rodanthe dealing with personal loss.
Linda Molloy appears as Jill Torrelson, who is connected to Robert's story of loss.
Pablo Schreiber takes the role of Charlie Torrelson, a family member coping with the ramifications of Robert's losses.
Mae Whitman plays Amanda Willis, one of Adrienne's children facing the family's emotional challenges.
Charlie Tahan portrays Danny Willis, Adrienne's son and the sibling of Amanda.
Carolyn McCormick plays Jenny, another member of the Rodanthe community.
Ted Manson appears as Old Gus, one of the local characters in the Rodanthe setting.
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