Robert De Niro plays Don Griffin, the father of the bride who is navigating the challenges of a complicated family dynamic during the wedding.
Diane Keaton portrays Ellie Griffin, the mother of the bride who has a unique history with her ex-husband, Don.
Amanda Seyfried plays Missy O'Connor, the bride-to-be who struggles with family complications on her wedding day.
Susan Sarandon takes on the role of Bebe McBride, a character who brings both wisdom and humor to the family gatherings.
Katherine Heigl plays Lyla Griffin, the daughter of Don and Ellie Griffin who is caught in the middle of family drama.
Topher Grace portrays Jared Griffin, the son of Don and Ellie who deals with personal issues while supporting his sister.
Robin Williams plays Father Monaghan, a priest who provides comedic relief amid the wedding chaos.
Ben Barnes portrays Alejandro Griffin, a foreign character who impacts the family dynamics as he prepares to marry Missy.
Christa Campbell plays Kim, a character whose interactions contribute to the overall family narrative.
Kyle Bornheimer portrays Andrew, a character associated with the wedding festivities and family interactions.
Christine Ebersole plays Muffin, contributing to the comedic elements of the family gathering.
David Rasche portrays Barry, adding to the mix of comedic and complicated relationships during the wedding.
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