Dan Aykroyd plays John W. Burns, Jr., a con artist who impersonates a psychiatrist and takes over a radio show.
Walter Matthau portrays Donald Becker, the real psychiatrist whom John W. Burns, Jr. impersonates.
Charles Grodin plays George Matlin, a radio producer caught up in the antics of John W. Burns, Jr.
Donna Dixon portrays Laura Rollins, a character involved in the schemes of John W. Burns, Jr.
Richard Romanus plays Harvey Michaels, a character within the radio show hijinks orchestrated by John W. Burns, Jr.
Mary Gross portrays Vera Matlin, a character entangled in the comedic web woven by John W. Burns, Jr.
David Clennon plays Lawrence Baird, a character affected by the antics of John W. Burns, Jr.
Arye Gross portrays Perry Kovin, a character within the web of deception spun by John W. Burns, Jr.
Victoria Jackson plays Robin, a character intertwined in the chaos caused by John W. Burns, Jr.
Michael DeLorenzo portrays Lopez, a character caught up in the antics brought on by John W. Burns, Jr.
Mickey Jones plays Watkins, a character affected by the consequences of John W. Burns, Jr.'s actions.
J.E. Freeman portrays Unger, a character within the realm of chaos instigated by John W. Burns, Jr.
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