Ralph Macchio portrays Eugene Martone, a young musician with a passion for blues guitar who embarks on a journey to learn from a legendary player.
Joe Seneca plays the character of Willie Brown, a blues musician who agrees to mentor Eugene Martone and teaches him the ways of the blues guitar.
Jami Gertz takes on the role of Frances, a character involved in Eugene Martone's journey in the world of blues music.
Joe Morton portrays Scratch's Assistant, a supporting role in the film who plays a part in Eugene's musical endeavors.
Robert Judd plays the character of Scratch, a pivotal figure in Eugene Martone's quest to master the blues guitar.
Steve Vai portrays Jack Butler, a guitar virtuoso who crosses paths with Eugene Martone in a musical showdown.
Tim Russ takes on the role of Robert Johnson, a character in the movie who is significant to the plot involving Eugene Martone.
Dennis Lipscomb plays Lloyd, a character who interacts with Eugene Martone during his musical journey in the film Crossroads.
Harry Carey, Jr. portrays the Bartender, a supporting character who is part of the world Eugene Martone navigates in the movie.
Otis Taylor is the Jookhouse Musician - Lead Guitar, a character who adds musical depth to the storyline of Crossroads.
Wally Taylor takes on the role of O.Z., a character who has a role to play in the events surrounding Eugene Martone in the film.
Allan Arbus portrays Dr. Santis, a character in the movie who contributes to the unfolding story of Eugene Martone and his musical pursuits.
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