Tom Berenger portrays Jake Taylor, a seasoned catcher who returns to the team to provide leadership and guidance.
Charlie Sheen plays Rick Vaughn, a talented but wild pitcher known for his powerful fastball.
Corbin Bernsen portrays Roger Dorn, the team's arrogant veteran third baseman.
Margaret Whitton plays Rachel Phelps, the team's new owner with a plan to relocate the franchise to Miami.
James Gammon portrays Lou Brown, the Indians' no-nonsense manager brought in to whip the team into shape.
Rene Russo plays Lynn Wells, the team's head of public relations and a potential love interest for Jake Taylor.
Wesley Snipes portrays Willie Mays Hayes, a speedy and flashy outfielder trying out for the team.
Charles Cyphers plays Charlie Donovan, the team's general manager overseeing player transactions.
Chelcie Ross portrays Eddie Harris, a crafty but aging pitcher relying on guile over strength.
Dennis Haysbert plays Pedro Cerrano, a power-hitting but superstitious outfielder who believes in voodoo.
Andy Romano plays Pepper Leach, the team's pitching coach focusing on developing the players' skills.
Bob Uecker portrays Harry Doyle, the Indians' entertaining and wisecracking radio broadcaster.
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