Renée Zellweger plays Anne Deveraux, Logan Lerman plays George Devereaux, Kevin Bacon plays Dan Devereaux, Troy Garity plays Becker, David Koechner plays Bill Massey, Eric McCormack plays Charlie, Chris Noth plays Dr. Harlan Williams, and Molly C. Quinn plays Paula.
My One and Only is a 2009 comedy-drama film loosely based on a story about George Hamilton's early life, as it follows a mother's unconventional journey with her two sons from New York to Hollywood in search of a new husband.