Wesley Snipes plays Nino Brown, a powerful drug lord who rises to prominence in the New York drug trade during the 1980s.
Ice-T portrays Scotty Appleton, a police officer determined to take down Nino Brown and his drug empire.
Allen Payne plays Garald 'Gee Money' Welles, Nino Brown's right-hand man who is deeply involved in the drug operation.
Chris Rock portrays Pookie, aformer drug addict who becomes a police informant.
Mario Van Peebles plays Stone, a detective who assists Scotty Appleton in his investigation.
Michael Michele portrays Selina, a woman involved with Nino Brown who struggles with her own choices.
Bill Nunn plays Duh Duh Duh Man, a character who is part of Nino Brown's drug operation.
Russell Wong portrays Park, a member of a rival gang that competes with Nino Brown.
Bill Cobbs plays Old Man, a character who provides advice and wisdom amidst the chaos.
Christopher Williams portrays Kareem Akbar, a key figure within the drug scene.
Judd Nelson plays Nick Peretti, a police officer who becomes entangled in the drug investigation.
Vanessa Williams portrays Keisha, a woman who is affected by the drug crisis in her community.
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