Dee Wallace portrays Karen White, a news anchor who experiences a traumatic event that leads her to a secluded colony of werewolves.
Patrick Macnee plays Dr. George Waggner, a psychiatrist who is involved in the investigation of the mysterious events in the film.
Dennis Dugan takes on the role of Chris, a close friend of Karen White who becomes entangled in the horror surrounding her.
Christopher Stone portrays R. William 'Bill' Neill, Karen's supportive husband who tries to help her through the terrifying ordeal she faces.
Belinda Balaski plays Terry Fisher, a colleague of Karen White who also gets drawn into the dangerous world of werewolves.
Kevin McCarthy appears as Fred Francis, a character involved in the investigation of the strange occurrences happening in the film.
John Carradine portrays Erle Kenton, an enigmatic character with a connection to the mysteries surrounding the werewolves.
Slim Pickens plays Sam Newfield, a resident of the colony who becomes a key figure in the unfolding events.
Elisabeth Brooks takes on the role of Marsha Quist, a seductive and dangerous member of the werewolf community.
Robert Picardo portrays Eddie Quist, a chilling character whose actions set off a chain of terrifying events in the film.
Margie Impert plays Donna, a character who becomes entangled in the dark secrets of the werewolves alongside Karen White.
Noble Willingham portrays Charlie Barton, a supporting character who plays a role in the unfolding horror faced by the cast of the movie.
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