This Is 40 Cast
The cast of This Is 40 including popularity data. Data for March 26, 2025.
Paul Rudd
as Pete

Paul Rudd plays the character Pete.

#1
Most popular actor on This Is 40
28,822 Wikipedia views yesterday
Leslie Mann
as Debbie

Leslie Mann portrays the character Debbie.

#9
Most popular actor on This Is 40
2,715 Wikipedia views yesterday
John Lithgow
as Oliver

John Lithgow takes on the role of Oliver.

#2
Most popular actor on This Is 40
9,923 Wikipedia views yesterday
Megan Fox
as Desi

Megan Fox appears as the character Desi.

#3
Most popular actor on This Is 40
7,663 Wikipedia views yesterday
Maude Apatow
as Sadie

Maude Apatow brings the character Sadie to life.

#12
Most popular actor on This Is 40
2,374 Wikipedia views yesterday
Iris Apatow
as Charlotte

Iris Apatow portrays the character Charlotte.

#14
Most popular actor on This Is 40
2,225 Wikipedia views yesterday
Chris O'Dowd
as Ronnie

Chris O'Dowd plays the character Ronnie.

#6
Most popular actor on This Is 40
3,698 Wikipedia views yesterday
Jason Segel
as Jason

Jason Segel portrays the character Jason.

#7
Most popular actor on This Is 40
3,373 Wikipedia views yesterday
Melissa McCarthy
as Catherine
#5
Most popular actor on This Is 40
4,047 Wikipedia views yesterday
Graham Parker
as Graham Parker
Albert Brooks
as Larry
#15
Most popular actor on This Is 40
1,613 Wikipedia views yesterday
Lena Dunham
as Cat
#10
Most popular actor on This Is 40
2,539 Wikipedia views yesterday
Annie Mumolo
as Barb
#21
Most popular actor on This Is 40
347 Wikipedia views yesterday
Robert Smigel
as Barry
#17
Most popular actor on This Is 40
990 Wikipedia views yesterday
Charlyne Yi
as Jodi
#16
Most popular actor on This Is 40
1,126 Wikipedia views yesterday
Lisa Darr
as Clair
#24
Most popular actor on This Is 40
108 Wikipedia views yesterday
Billie Joe Armstrong
as Billie Joe Armstrong
#11
Most popular actor on This Is 40
2,462 Wikipedia views yesterday
Michael Ian Black
as Accountant
#18
Most popular actor on This Is 40
712 Wikipedia views yesterday
Wyatt Russell
as Flirty Hockey Player
#4
Most popular actor on This Is 40
5,432 Wikipedia views yesterday
Tom Yi
as Charlotte's Teacher
Tim Bagley
as Dr. Pellegrino
#19
Most popular actor on This Is 40
430 Wikipedia views yesterday
Ava Sambora
as Wendy
Megan Grano
as School Playdate Parent
#28
Most popular actor on This Is 40
3 Wikipedia views yesterday
D.A. Sandoval
as Older Pregnant Parent
Derek Basco
as Room Service Waiter
Nicol Paone
as E.R. Nurse
#25
Most popular actor on This Is 40
15 Wikipedia views yesterday
Lynne Alana Delaney
as Disturbed Restaurant Patron (uncredited)
Katia Kieling
as BBQ Guest (uncredited)
Bill Hader
as Desi's Store Pickup (uncredited)
#8
Most popular actor on This Is 40
3,240 Wikipedia views yesterday
Tom Everett
as Pete's Doctor
#23
Most popular actor on This Is 40
144 Wikipedia views yesterday
Tatum O'Neal
as Realtor
#13
Most popular actor on This Is 40
2,318 Wikipedia views yesterday
Ryan Adams
as Ryan Adams
Jessica Lee
as Party Guest #1 (uncredited)
#27
Most popular actor on This Is 40
8 Wikipedia views yesterday
Rebekka Johnson
as Gyno Nurse
#26
Most popular actor on This Is 40
9 Wikipedia views yesterday
Johnny Pemberton
as Room Service Waiter
#20
Most popular actor on This Is 40
371 Wikipedia views yesterday
Dan Bakkedahl
as Dentist
#22
Most popular actor on This Is 40
179 Wikipedia views yesterday
For the best insights and data about This Is 40, visit our main This Is 40 page.