Dopesick (TV) Cast
The cast of Dopesick. Updated on September 18, 2025.
46 actors
Michael Keaton
as Samuel Finnix (8 episodes)

Michael Keaton portrays Dr. Samuel Finnix, a caring doctor who becomes entangled with the opioid crisis.

Peter Sarsgaard
as Rick Mountcastle (8 episodes)

Peter Sarsgaard plays Rick Mountcastle, a federal prosecutor investigating the company behind OxyContin.

Michael Stuhlbarg
as Richard Sackler (8 episodes)

Michael Stuhlbarg takes on the role of Richard Sackler, the ambitious executive of Purdue Pharma.

Kaitlyn Dever
as Betsy Mallum (8 episodes)

Kaitlyn Dever embodies Betsy Mallum, a young miner grappling with addiction.

Will Poulter
as Billy Cutler (8 episodes)

Will Poulter plays Billy Cutler, an aggressive sales rep pushing OxyContin to doctors.

Rosario Dawson
as Bridget Meyer (8 episodes)

Rosario Dawson portrays Bridget Meyer, a DEA agent working to unveil the company's questionable practices.

John Hoogenakker
as Randy Ramseyer (8 episodes)

John Hoogenakker appears as Randy Ramseyer, an assistant U.S. Attorney in the investigation.

Will Chase
as Michael Friedman (8 episodes)

Will Chase plays Michael Friedman, a Purdue Pharma executive involved in marketing OxyContin.

Andrea Powell
as Sharon Burnham (1 episode)

Andrea Powell takes the part of Sharon Burnham, a sales manager at Purdue Pharma.

Ryan Paynter
as Teen (1 episode)

Ryan Paynter portrays a troubled teen caught up in the opioid epidemic.

Jaime Ray Newman
as Kathe Sackler (5 episodes)

Jaime Ray Newman plays Kathe Sackler, a member of the Purdue Pharma owning family.

Rebecca Wisocky
as Cynthia McCormick (3 episodes)

Rebecca Wisocky embodies Cynthia McCormick, an employee at the FDA reviewing OxyContin.

Mare Winningham
as Diane Mallum (7 episodes)
Ian Unterman
as Jonathan Sackler (7 episodes)
Jake McDorman
as John Brownlee (7 episodes)
Phillipa Soo
as Amber Collins (7 episodes)
Brendan Patrick Connor
as Howard Udell (7 episodes)
Andrea Frankle
as Beth Sackler (7 episodes)
Lawrence Arancio
as Raymond Sackler (5 episodes)
Arischa Conner
as Leah Turner (6 episodes)
Raúl Esparza
as Paul Mendelson (5 episodes)
Winsome Brown
as Theresa Sackler (6 episodes)
Andrés Erickson
as Mortimer D.A. Sackler (6 episodes)
Ray McKinnon
as Jerry Mallum (5 episodes)
Cleopatra Coleman
as Grace Pell (5 episodes)
Deadra Moore
as Karen Johnson (5 episodes)
Alayna Hester
as Elizabeth Ann McClung (5 episodes)
Carolee Carmello
as Drea Price (3 episodes)
Rick Espaillat
as Dr. Alan Spanos (4 episodes)
Amy Parrish
as Judy Cohen (1 episode)
Adam Fristoe
as James Comey (1 episode)
Aaron Serotsky
as David Haddox (3 episodes)
Caitlin Mehner
as Paula Greene (2 episodes)
Nicholas Logan
as Walt (2 episodes)
Mark Jacoby
as Dr. Hershel Jick (1 episode)
Tricia Hawn
as Shelly Finnix (1 episode)
Audrey Moore
as Maureen Sara (1 episode)
Austin Freeman
as Grant Simmons (2 episodes)
Erin Dangler
as Marianne Skolek (2 episodes)
Paden Fallis
as Louis Melton (2 episodes)
Spencer Garrett
as Larry Berger (1 episode)
Trevor Long
as Rudy Giuliani (1 episode)
Meagen Fay
as Sister Beth Davies (2 episodes)
Amy Rutberg
as Alice Fisher (1 episode)
Kenneth Tigar
as Arthur Sackler (2 episodes)
Helen Goldsby
as Regina Carter (2 episodes)
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