Kurt Russell plays Snake Plissken, a tough and resourceful ex-soldier turned criminal tasked with rescuing the President from a maximum-security prison in post-apocalyptic Manhattan.
Lee Van Cleef portrays Police Commissioner Bob Hauk, who enlists Snake Plissken to undertake the dangerous mission of saving the President from New York City.
Ernest Borgnine plays Cabbie, a jovial taxi driver in the chaotic cityscape of New York who aids Snake Plissken in navigating the treacherous urban terrain.
Donald Pleasence portrays the President of the United States, whose life is imperiled after his plane crash-lands in the crime-ridden wasteland of Manhattan.
Isaac Hayes appears as The Duke of New York, the powerful and ruthless leader of the criminal underground in Manhattan, who holds the President captive.
Season Hubley plays the Girl in Chock Full O'Nuts, a character encountered by Snake Plissken during his perilous mission in the dystopian realm of New York City.
Harry Dean Stanton portrays Harold 'Brain' Helman, an intelligent and cunning inmate of New York City who assists Snake Plissken in navigating the city's dangers.
Adrienne Barbeau plays Maggie, a tough and resourceful character who joins forces with Snake Plissken in his mission to rescue the President from the confines of Manhattan.
Tom Atkins appears as Rehme, a supporting character in the film who aids Snake Plissken in his efforts to navigate the hazardous urban landscape of Manhattan.
Charles Cyphers portrays the Secretary of State, a governmental official caught in the volatile situation of having the President endangered in the perilous cityscape of New York.
Frank Doubleday plays Romero, a menacing and dangerous criminal who operates within the lawless and chaotic environment of Manhattan in the film Escape from New York.
John Strobel portrays Cronenberg, a character in the movie who navigates the dangerous and unpredictable world of Manhattan alongside Snake Plissken and other eclectic personalities.
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