Innerspace

Dennis Quaid portrays Lt. Tuck Pendleton, a pilot who volunteers to be miniaturized and injected into a rabbit as part of a scientific experiment.

Martin Short plays Jack Putter, a hypochondriac who becomes unwittingly involved in the experiment when Tuck's pod is injected into him.

Meg Ryan stars as Lydia Maxwell, Tuck's journalist ex-girlfriend who gets caught up in the adventure.

Kevin McCarthy appears as Victor Eugene Scrimshaw, a ruthless industrialist trying to get his hands on the technology behind miniaturization.

Fiona Lewis portrays Dr. Margaret Canker, a scientist involved in the experiment with Tuck and Jack.

Vernon Wells plays Mr. Igoe, one of Scrimshaw's henchmen who cause trouble for the protagonists.

Robert Picardo appears as The Cowboy, a mysterious individual encountered by Tuck inside Jack's body.

Dick Miller plays Cab Driver, a character who unwittingly becomes part of the chaotic journey inside Jack's body.

Wendy Schaal portrays Wendy, Jack's colleague who helps him during his bizarre predicament.

Harold Sylvester plays Pete Blanchard, a friend of Jack who gets caught up in the adventure.

William Schallert appears as Dr. Greenbush, a scientist involved in the miniaturization experiment.

Henry Gibson portrays Mr. Wormwood, another character involved in the machinations surrounding miniaturization technology.