Osmosis Jones Cast
The cast of Osmosis Jones including popularity data. Data for December 21, 2024.
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Chris Rock
as Osmosis Jones (voice)

Chris Rock lends his voice to the character of Osmosis Jones.

#4
Most popular actor on Osmosis Jones
3,252 Wikipedia views yesterday
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Laurence Fishburne
as Thrax (voice)

Laurence Fishburne voices the character of Thrax.

#5
Most popular actor on Osmosis Jones
3,015 Wikipedia views yesterday
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David Hyde Pierce
as Drix (voice)

David Hyde Pierce voices the character of Drix.

#9
Most popular actor on Osmosis Jones
1,658 Wikipedia views yesterday
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Brandy Norwood
as Leah (voice)

Brandy Norwood lends her voice to the character of Leah.

#6
Most popular actor on Osmosis Jones
3,010 Wikipedia views yesterday
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Bill Murray
as Frank Detorre

Bill Murray portrays the character of Frank Detorre.

#1
Most popular actor on Osmosis Jones
6,892 Wikipedia views yesterday
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Molly Shannon
as Mrs. Boyd

Molly Shannon portrays the character of Mrs. Boyd.

#7
Most popular actor on Osmosis Jones
2,849 Wikipedia views yesterday
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William Shatner
as Mayor Phlegmming (voice)

William Shatner lends his voice to the character of Mayor Phlegmming.

#2
Most popular actor on Osmosis Jones
6,177 Wikipedia views yesterday
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Ron Howard
as Tom Colonic (voice)

Ron Howard provides the voice for the character of Tom Colonic.

#3
Most popular actor on Osmosis Jones
5,145 Wikipedia views yesterday
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Sherry Lynn
as (voice)
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Mickie McGowan
as Additional Character Voice (voice)
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Chris Elliott
as Bob
#10
Most popular actor on Osmosis Jones
1,419 Wikipedia views yesterday
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Elena Franklin
as Shane Detorre
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Kid Rock
as Kidney Rock
#8
Most popular actor on Osmosis Jones
2,420 Wikipedia views yesterday
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Uncle Kracker
as Kidney Rock (voice)
#14
Most popular actor on Osmosis Jones
351 Wikipedia views yesterday
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Carlos Alazraqui
as Additional Character Voices (voice)
#11
Most popular actor on Osmosis Jones
555 Wikipedia views yesterday
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Rodger Bumpass
as Additional Character Voice (voice)
#12
Most popular actor on Osmosis Jones
522 Wikipedia views yesterday
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Richard Steven Horvitz
as Additional Character Voice (voice)
#13
Most popular actor on Osmosis Jones
433 Wikipedia views yesterday
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Danny Mann
as Additional Character Voice (voice)
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Mickie McGowan
as Additional Character Voices (voice)
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Jonathan Adams
as Additional Character Voice
For the best insights and data about Osmosis Jones, visit our main Osmosis Jones page.