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Osmosis Jones

Osmosis Jones Cast

86 cast members · 37 with popularity data
#2,127 movie today
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Most Popular Osmosis Jones Cast Members

William Shatner is currently the most popular Osmosis Jones cast member online with an Attention Score of 4.5. 1 of 86 cast members rank in the top 1,000 actors online today. Updated October 21, 2026.

1
William Shatner
Mayor Phlegmming (voice)
4.5
#889 overall
2
Bill Murray
Frank Detorre
4.2
#1,010 overall
3
Kid Rock
Kidney Rock (voice)
3.6
#1,234 overall
4
Ron Howard
Tom Colonic (voice)
3.5
#1,288 overall
5
Laurence Fishburne
Thrax (voice)
2.7
#1,881 overall
6
Chris Rock
Osmosis Jones (voice)
2.4
#2,239 overall
7
Brandy Norwood
Leah (voice)
1.6
#3,725 overall
8
David Hyde Pierce
Drix (voice)
1.6
#3,726 overall
9
Chris Elliott
Bob
1.5
#3,837 overall
10
Molly Shannon
Mrs. Boyd
1.2
#5,077 overall
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11
Richard Steven Horvitz
Additional Character Voices (voice)
0.5
#10,016 overall
12
Robert Wisdom
Big Germ (voice)
0.5
#10,365 overall
13
Carlos Alazraqui
Spanish Germ (voice)
0.4
#12,265 overall
14
Uncle Kracker
Kidney Rock Band (voice)
0.4
#12,616 overall
15
Anne Lockhart
Female Red Blood Cell (voice)
0.4
#13,555 overall
16
Rodger Bumpass
Joe Cramp / Announcer for Nerve News Network (voice)
0.3
#14,134 overall
17
Joel Silver
Police Chief (voice) (uncredited)
0.3
#15,727 overall
18
Antonio Fargas
Chill the Flu Shot (voice)
0.3
#16,117 overall
19
Joe C.
Kidney Rock Band (voice)
0.3
#16,555 overall
20
Jonathan Adams
Officer Tom (voice)
0.2
#17,254 overall
21
Zak Penn
ER Doctor #3
0.2
#17,769 overall
22
Rif Hutton
Charlie (voice)
0.2
#19,376 overall
23
John Melendez
Artie (voice)
0.2
#21,938 overall
24
Zen Gesner
ER Doctor #1
0.1
#28,372 overall
25
Steve Susskind
Mob Boss Germ (voice)
0.1
#29,932 overall
26
Eddie Frierson
Frank Police Department Officer (voice)
0.1
#30,320 overall
27
Donald Fullilove
Doughnut (voice)
0.1
#35,242 overall
28
Eddie Barth
Conductor (voice)
0.0
#38,826 overall
29
Chris Phillips
Firefighter Doug (voice)
0.0
#39,130 overall
30
Paul Pape
Male Red Blood Cell #2 (voice)
0.0
#39,564 overall
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31
Sherry Lynn
Trudy (voice)
0.0
#40,178 overall
32
Doug Stone
Police Officer Jamie (voice)
0.0
#40,384 overall
33
David Ossman
Scabies (voice) (uncredited)
0.0
#43,789 overall
34
Paul Christie
Dan Matter / Germ (voice)
0.0
#45,855 overall
35
Marc Hyman
ER Doctor #2
0.0
#46,400 overall
36
Danny Murphy
Zookeeper Superintendent
0.0
#58,385 overall
37
Al Rodrigo
Frank Police Department Walkie Talkie (voice)
0.0
#62,351 overall
38
Elena Franklin
Shane Detorre
—
39
Mickie McGowan
Additional Character Voice (voice)
—
40
Keith Anthony
Additional Character Voices (voice)
—
41
Sally Brooks
Additional Character Voices (voice)
—
42
Michael Carven
Additional Character Voices (voice)
—
43
Janis Dardaris
Additional Character Voices (voice)
—
44
Wendy Dillon
Additional Character Voices (voice)
—
45
Jackie Gonneau
Additional Character Voices (voice)
—
46
Shannon Gregory
Additional Character Voices (voice)
—
47
Art Kimbro
Additional Character Voices (voice)
—
48
Joyce Kurtz
Additional Character Voices (voice)
—
49
Danny Mann
Musician Cell (voice)
—
50
Kenny Olson
Kidney Rock Band (voice)
—
51
Jason Krause
Kidney Rock Band (voice)
—
52
Stefanie Eulinberg
Kidney Rock Band (voice)
—
53
Jimmie Bones
Kidney Rock Band (voice)
—
54
Héctor Mercado
Additional Character Voices (voice)
—
55
Marilyn Pasekoff
Additional Character Voices (voice)
—
56
Lynne Redding
Additional Character Voices (voice)
—
57
Herschel Sparber
Bruiser (voice)
—
58
Keri Tombazian
Additional Character Voices (voice)
—
59
Paul Tuerpe
Additional Character Voices (voice)
—
60
Jack McCullough
Zookeeper
—
61
Will Dunn
Oyster Boy
—
62
Jackie Flynn
School Janitor
—
63
Kelsey Jordan
Bus Girl #1
—
64
Abe Farrelly
Bus Girl #2
—
65
Jesse Peter
Laughing Boy
—
66
John-Eliot Jordan
Pea Soup Manager
—
67
Nancy Byers
Pea Soup Supervisor
—
68
Kevin J. Flynn
Docky's Clamshack Waiter
—
69
Sean Gildea
Dreamy Photographer
—
70
Kathryn Frick
Nurse #1
—
71
Nikki Tyler-Flynn
Nurse #2
—
72
Elizabeth Jordan
Nurse #3
—
73
Diane Conrad
Zoo Visitor or Staff
—
74
Judith Conrad
Zoo Visitor or Staff
—
75
Thomas Jordan
The Zoo Visitor or Staff
—
76
Sydney J. Bartholomew Jr.
Zoo Visitor or Staff
—
77
Erica Johnson
Zoo Visitor or Staff
—
78
Bo Cleary
Pea Soup Staff
—
79
Bruce McIntyre
Pea Soup Staff
—
80
Colleen O'Donnell
Docky's Clamshack
—
81
Docky
The Bikini Gang
—
82
Joe Murphy
The Bikini Gang
—
83
Brian Mone
Police Officer
—
84
Sean Fitzgerald
Police Officer
—
85
Grace Costa
ER Nurse
—
86
Emily O’Donnell
School Girl
—
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