Dustin Hoffman plays Sam Daniels, a senior disease control officer who investigates the outbreak of a dangerous virus.
Rene Russo portrays Robby Keough, a skilled Army scientist and the romantic interest of Sam Daniels.
Morgan Freeman plays General Billy Ford, a military leader involved in managing the response to the viral outbreak.
Kevin Spacey takes on the role of Casey Schuler, a member of Sam Daniels' team who assists in the crisis.
Cuba Gooding Jr. portrays Major Salt, a military officer working alongside General Ford.
Donald Sutherland plays General Donald McClintock, a government official concerned with the outbreak's containment.
Patrick Dempsey portrays Jimbo Scott, a character who plays a key role in the unfolding crisis.
Zakes Mokae plays Dr. Benjamin Iwabi, a scientist involved in researching the virus.
Malick Bowens takes on the role of Dr. Raswani, a medical professional dealing with the epidemic's impact.
Susan Lee Hoffman portrays Dr. Lisa Aronson, a doctor working to find a solution to the outbreak.
Benito Martinez plays Dr. Julio Ruiz, a medical expert contributing to the efforts against the virus.
Bruce Jarchow takes on the role of Dr. Mascelli, a physician involved in the emergency response.
Our free email delivers the daily top 10 TV shows and top 10 movies directly to your inbox. Stay ahead of the trends. Sign up below.