The Big Sick Cast
The cast of The Big Sick.
Kumail Nanjiani
as Kumail Nanjiani

Kumail Nanjiani plays the role of Kumail Nanjiani, the protagonist of the film. He is a stand-up comedian and actor.

Zoe Kazan
as Emily Gardner

Zoe Kazan portrays the character of Emily Gardner, the love interest of Kumail. She is an American actress and screenwriter.

Holly Hunter
as Beth Gardner

Holly Hunter plays the role of Beth Gardner, Emily's mother. She is an acclaimed American actress.

Ray Romano
as Terry Gardner

Ray Romano portrays the character of Terry Gardner, Emily's father. He is an American comedian and actor.

Anupam Kher
as Azmat Nanjiani

Anupam Kher plays the role of Azmat Nanjiani, Kumail's father. He is an Indian actor and former chairman of the Film and Television Institute of India.

Zenobia Shroff
as Sharmeen Nanjiani

Zenobia Shroff portrays the character of Sharmeen Nanjiani, Kumail's mother. She is an Indian-American actress.

Adeel Akhtar
as Naveed Nanjiani

Adeel Akhtar plays the role of Naveed Nanjiani, Kumail's brother. He is a British actor.

Bo Burnham
as CJ

Bo Burnham portrays the character of CJ, Kumail's fellow stand-up comedian. He is an American comedian, musician, actor, and filmmaker.

Aidy Bryant
as Mary
Kurt Braunohler
as Chris
Vella Lovell
as Khadija
Myra Lucretia Taylor
as Nurse Judy
Jeremy Shamos
as Bob Dalavan
David Alan Grier
as Andy Dodd
Ed Herbstman
as Sam Highsmith
Shenaz Treasury
as Fatima Nanjiani
Rebecca Naomi Jones
as Jesse
Kuhoo Verma
as Zubeida
Mitra Jouhari
as Yazmin
Celeste Arias
as Denise
Shana Solomon
as Nurse Bette
Jeff Blumenkrantz
as Dr. Wright
Linda Emond
as Dr. Cunningham
Holly Chou
as Dr. Whelan
Andrew Pang
as Dr. Spellman
Alison Cimmet
as Dr. Platt
Lawrence Ballard
as Dr. Lewin
Shunori Ramanathan
as Sumera
Spencer House
as Racist Heckler
Susham Bedi
as Tina (Khadija's Mother)
Rahul Bedi
as Farhan (Khadija's Father)
Matthew Cardarople
as Fast Food Cashier
Myra Turley
as Waiting Room Person 1
William Stephenson
as Waiting Room Person 2
Marilyn Torres
as Waiting Room Person 3
Kerry Flanagan
as Waiting Room Person 4
Jack O'Connell
as Waiting Room Person 5
Charles Gould
as Waiting Room Person 6
Isabel Shill
as Party Goer 1
Lauren Patten
as Party Goer 2
Keilly McQuail
as Party Goer 3
Zach Cherry
as Party Goer 4
Jack Corrigan
as Restaurant Boy (uncredited)
Sophia Muller
as Chrissy (uncredited)
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