Cast of I Know This Much Is True

Mark Ruffalo plays the dual roles of Dominick Birdsey and Thomas Birdsey in I Know This Much Is True. Dominick is a complex character dealing with his own personal demons while also caring for his mentally ill brother, Thomas. Thomas, who suffers from schizophrenia, presents a unique set of challenges for Dominick as he tries to protect and support his brother. Ruffalo's performance showcases his versatility and ability to portray the emotional depth of both characters.

Melissa Leo portrays Concettina Ipolita Tempesta 'Ma' Birdsey in I Know This Much Is True. Ma Birdsey is the matriarch of the Birdsey family and a source of strength for her sons, Dominick and Thomas. Leo's performance captures the resilience and love that Ma Birdsey exhibits as she navigates the difficulties faced by her family. Melissa Leo's portrayal brings depth and authenticity to the character of Ma.

Rosie O'Donnell takes on the role of Lisa Sheffer in I Know This Much Is True. Lisa is a social worker who becomes involved in Dominick and Thomas' lives as she tries to help them navigate their challenges. O'Donnell's performance as Lisa showcases her ability to bring both warmth and determination to the character, providing support and guidance to the Birdsey brothers.

Archie Panjabi portrays Dr. Patel in I Know This Much Is True. Dr. Patel is a psychiatrist who plays a significant role in the lives of Dominick and Thomas Birdsey. Panjabi's performance brings intelligence and compassion to the character, as she works with the brothers to understand and manage their mental health issues. Archie Panjabi's portrayal adds depth and empathy to Dr. Patel.

Kathryn Hahn takes on the role of Dessa Constantine in I Know This Much Is True. Dessa is Dominick's ex-wife and the mother of his child. Hahn's performance captures the complex dynamics of their relationship and the challenges they face while co-parenting. Kathryn Hahn's portrayal adds depth and complexity to the character of Dessa.

John Procaccino portrays Ray Birdsey in I Know This Much Is True. Ray is Dominick and Thomas' stepfather and a supportive figure in their lives. Procaccino's performance captures Ray's empathy and understanding as he tries to guide the Birdsey brothers through their struggles. John Procaccino brings authenticity and compassion to the character of Ray.

Rob Huebel plays the character of Leo in I Know This Much Is True. Leo is a close friend of Dominick's and a source of humor and support in his life. Huebel's performance brings levity and warmth to the character, providing a balance to the emotional intensity of the series.

Michael Greyeyes portrays Ralph Drinkwater in I Know This Much Is True. Ralph is a childhood friend of Dominick and Thomas and plays a significant role as their paths intertwine. Greyeyes' performance showcases the complexity of Ralph's character, adding depth and intrigue to the series.