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I Know This Much Is True

I Know This Much Is True Cast

80 cast members · 27 with active Buzz Score
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Most Popular I Know This Much Is True Cast Members

Juliette Lewis is currently the most popular I Know This Much Is True cast member online with a Buzz Score of 5.3. 2 of 80 cast members rank in the top 1,000 actors online today. Updated June 11, 2026.

Today's Most Popular Cast
#1
Juliette Lewis
as Nedra Frank
5.3
#548 overall
#2
Mark Ruffalo
as Dominick Birdsey / Thomas Birdsey
4.9
#636 overall
#3
Rosie O'Donnell
as Lisa Sheffer
2.4
#2,026 overall
Full Cast Ranked
June 11, 2026
1
Juliette Lewis
Nedra Frank · 2 eps
5.3
#548 overall
2
Mark Ruffalo
Dominick Birdsey / Thomas Birdsey · 6 eps
4.9
#636 overall
3
Rosie O'Donnell
Lisa Sheffer · 6 eps
2.4
#2,026 overall
4
Destry Allyn Spielberg
Dr. Hume's Daughter · 1 eps
2.0
#2,688 overall
5
Kathryn Hahn
Dessa Constantine · 6 eps
1.9
#2,873 overall
6
Imogen Poots
Joy Hanks · 3 eps
1.8
#3,024 overall
7
Archie Panjabi
Dr. Patel · 6 eps
1.3
#4,233 overall
8
Melissa Leo
Concettina Ipolita Tempesta 'Ma' Birdsey · 6 eps
1.2
#4,575 overall
9
Bruce Greenwood
Dr. Hume · 2 eps
1.2
#4,931 overall
10
Aisling Franciosi
Young Dessa Constantine · 2 eps
1.0
#5,746 overall
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11
Tatanka Means
Nabby Drinkwater · 2 eps
0.9
#6,585 overall
12
Harris Yulin
Father Lavie · 1 eps
0.5
#9,713 overall
13
Guillermo Díaz
Sergeant Mercado · 1 eps
0.4
#11,899 overall
14
Laura Silverman
Kristin · 1 eps
0.4
#12,224 overall
15
Felix Solis
Nurse · 1 eps
0.3
#13,513 overall
16
Rob Huebel
Leo · 6 eps
0.3
#14,828 overall
17
Michael Greyeyes
Ralph Drinkwater · 6 eps
0.2
#19,667 overall
18
Brian Goodman
Al · 1 eps
0.2
#20,906 overall
19
Philip Ettinger
Early Adulthood Dominick Birdsey / Thomas Birdsey · 2 eps
0.1
#25,036 overall
20
Joe Grifasi
Steve Falice · 1 eps
0.1
#27,224 overall
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21
Marylouise Burke
Librarian · 1 eps
0.1
#27,423 overall
22
Brandon J. Dirden
Kyle's Dad · 1 eps
0.1
#31,174 overall
23
Marcello Fonte
Domenico Onofrio Tempesta · 2 eps
0.0
#48,586 overall
24
Christopher J. Hanke
Thad · 1 eps
0.0
#52,280 overall
25
Laura Esterman
Ruth Hood · 3 eps
0.0
#53,641 overall
26
Gina Costigan
Mrs. O'Meara · 1 eps
0.0
#54,723 overall
27
Michael Genet
Thomas' Surgeon · 1 eps
0.0
#56,296 overall
28
John Procaccino
Ray Birdsey · 6 eps
·
29
Gabe Fazio
Shawn Tudesco / Dominick and Thomas Acting Double · 6 eps
·
30
Sue Jean Kim
Dr. Yup · 1 eps
·
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31
Michael Simon Hall
Stuart Feinstein · 1 eps
·
32
Steven Cox
Boyfriend of Dr. Hume's Daughter · 1 eps
·
33
MorningStar Angeline
Nabby Drinkwater's Wife · 1 eps
·
34
Al Linea
Abruzzi · 1 eps
·
35
Richard Fitch
Mill Foreman · 1 eps
·
36
Amy Lynn Stewart
Merciful Mother · 1 eps
·
37
Tim Ruddy
Robocop · 1 eps
·
38
Sandra Berrios
Social Worker at Hatch · 1 eps
·
39
Christine Parks
Humanities Department Chair · 1 eps
·
40
Morgan Sullivan
Office Buddy · 1 eps
·
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41
Jake Robards
Landlubbers (voice) · 1 eps
·
42
María Gonzalez
Ma's Oncology Nurse · 1 eps
·
43
A.C. Peterson
Gene Diogenes · 1 eps
·
44
James Quattrochi
Bus Driver · 1 eps
·
45
Rachel B. Joyce
Jeanette · 1 eps
·
46
Paul Coleman
Support Group Counselor · 1 eps
·
47
Katt Masterson
Doreen · 1 eps
·
48
Jason Furlani
Larry Penn · 1 eps
·
49
Annie Fitzgerald
Miss Hanker · 2 eps
·
50
Kate Grimes
English Professor · 1 eps
·
51
Joseph Ragno
Henrey Rood · 1 eps
·
52
Acahkos Johnson
Penny Ann Drinkwater · 2 eps
·
53
Jaiden Klein
Marie Sexton · 2 eps
·
54
Charlie Reina
Channy · 2 eps
·
55
Violet Adams
Bunny Borsa · 2 eps
·
56
Oliver Patnode
Otero · 2 eps
·
57
Chelsea Sheets
Brunette · 1 eps
·
58
Matt Helm
Young Leo · 2 eps
·
59
Derek Goh
17-19 Year Old Dominick & Thomas Acting Double · 2 eps
·
60
Raymond Neil Hernandez
Omar · 1 eps
·
61
Simone Coppo
Vincenzo Tempesta · 1 eps
·
62
Sean Cullen
Dr. Yates · 1 eps
·
63
Federico Dordei
Nunzio Tucci · 1 eps
·
64
Agatha Nowicki
Angie Constantine · 2 eps
·
65
Rocco Masihi
Young Thomas Birdsey · 4 eps
·
66
Irene Muscara
Prosperina Tucci · 2 eps
·
67
Adrienne R. Williams
Mrs. Birdsall · 2 eps
·
68
Shannon Plumb
Charlotte · 1 eps
·
69
Donnie Masihi
Young Dominick Birdsey · 4 eps
·
70
Zaria Degenhardt
11 Year Old Concettina · 1 eps
·
71
Mark A. Gamma
Mourner Mark · 1 eps
·
72
Wayne J. Miller
Mourner Wayne · 1 eps
·
73
Thomas Gionet-Lavigne
Ray's Orderly · 1 eps
·
74
Alexander Hacker
Templeton · 1 eps
·
75
Robert Mladinich
Paddy Wagon Officer · 1 eps
·
76
Roberta Riganò
Ignazia Tempesta · 1 eps
·
77
Tim Ruddy
Robocop · 1 eps
·
78
Ethan Crystal
Thin Sailor · 1 eps
·
79
James Pravasilis
Third Guard · 1 eps
·
80
Michael Armand DeMatteo
Fatso · 1 eps
·
televisionstats.com
Cast Popularity FAQ
Who is the most popular I Know This Much Is True cast member right now?
Juliette Lewis is currently the most popular I Know This Much Is True cast member online, with a Buzz Score of 5.3 and an overall actor rank of #548 as of June 11, 2026.
How many cast members does I Know This Much Is True have?
I Know This Much Is True has 80 credited cast members. 27 of them have an active Buzz Score on Television Stats today.
Which I Know This Much Is True cast member has the highest career peak?
Kathryn Hahn has the highest Peak Buzz Score among the I Know This Much Is True cast, reaching 36.1 at their career high.
How many I Know This Much Is True cast members are in the top 1,000 actors today?
2 of the 80 I Know This Much Is True cast members currently rank within the top 1,000 most popular actors online on Television Stats.
televisionstats.com
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