Michael Douglas portrays Detective Nick Curran, a troubled police officer investigating the murder of a former rock star. Curran becomes entangled in a complex relationship with the enigmatic Catherine Tramell.
Sharon Stone plays Catherine Tramell, a seductive and manipulative crime novelist who becomes the prime suspect in a murder case that Detective Nick Curran is investigating.
George Dzundza appears as Gus Moran, Nick Curran's police partner who is wary of Curran's involvement with the mysterious Catherine Tramell.
Jeanne Tripplehorn takes on the role of Dr. Beth Garner, a police psychologist who becomes romantically involved with Detective Nick Curran while aiding him in the murder investigation.
Leilani Sarelle portrays Roxy, a woman with a connection to Catherine Tramell who becomes involved in the murder investigation.
Denis Arndt plays Lieutenant Philip Walker, a high-ranking officer who oversees the murder case that Detective Nick Curran is working on.
Bruce A. Young appears as Andrews, a member of the police department involved in the murder investigation alongside Detective Nick Curran.
Chelcie Ross portrays Captain Talcott, a senior officer in the police department who oversees the murder investigation that Detective Nick Curran is part of.
Dorothy Malone takes on the role of Hazel Dobkins, a character connected to the murder case that Detective Nick Curran is investigating.
Wayne Knight plays John Correli, a character involved in the murder investigation that Detective Nick Curran is leading.
Daniel von Bargen appears as Lieutenant Marty Nilsen, part of the police team investigating the murder case alongside Detective Nick Curran.
Stephen Tobolowsky portrays Dr. Lamott, a character linked to the murder investigation that Detective Nick Curran is involved in.
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