Zach Galligan portrays Billy Peltzer, the main protagonist of the film who receives a Mogwai named Gizmo as a Christmas present.
Phoebe Cates plays Kate Beringer, Billy's girlfriend who works as a bartender and gets caught up in the chaos caused by the mischievous Gremlins.
Hoyt Axton portrays Randall Peltzer, Billy's father who gifts him the Mogwai and inadvertently sets off a chain of events.
Frances Lee McCain plays Lynn Peltzer, Billy's mother who also gets embroiled in the mayhem caused by the Gremlins.
Corey Feldman portrays Pete Fountaine, a young boy who is a friend of Billy and gets involved in the battle against the mischievous creatures.
Keye Luke plays Grandfather (Mr. Wing), the original owner of Gizmo who warns Billy about the responsibility that comes with caring for the Mogwai.
John Louie plays the Chinese Boy, a character who has a brief but pivotal role in the film involving the backstory of Gizmo.
Dick Miller portrays Murray Futterman, a neighbor of Billy who faces off against the mischievous Gremlins in his effort to protect his home.
Jackie Joseph plays Sheila Futterman, Murray's wife who also encounters the chaos caused by the Gremlins in their town.
Polly Holliday portrays Ruby Deagle, a mean-spirited wealthy woman in the town who clashes with both Billy and the mischievous creatures.
Judge Reinhold plays Gerald Hopkins, an ambitious and somewhat arrogant character who works in the local bank in the town.
Edward Andrews portrays Mr. Corben, a character in the film who has a minor role in the unfolding events involving the Gremlins.
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