Robert De Niro portrays The Creature, also known as the Sharp Featured Man, seeking acceptance and grappling with his existence.
Kenneth Branagh plays the ambitious scientist Victor Frankenstein, who becomes obsessed with creating life from death.
Tom Hulce takes on the role of Henry Clerval, Victor Frankenstein's loyal friend and confidant.
Helena Bonham Carter embodies Elizabeth, the beloved fiancée of Victor Frankenstein caught in the midst of his scientific obsession.
Aidan Quinn portrays Captain Robert Walton, the explorer who rescues Victor Frankenstein in the icy Arctic and listens to his tale.
Ian Holm plays Baron Frankenstein, Victor's supportive father who witnesses the dark consequences of his son's actions.
Richard Briers appears as Grandfather, a character who brings warmth and wisdom to the story.
John Cleese takes on the role of Prof. Waldman, a mentor to Victor Frankenstein who encourages his scientific pursuits.
Robert Hardy portrays Prof. Krempe, an academic figure skeptical of Victor Frankenstein's radical ideas.
Cherie Lunghi plays Caroline Beaufort Frankenstein, Victor's caring mother who passes away early in the film.
Celia Imrie appears as Mrs. Moritz, a character entangled in the tragedies that unfold within the Frankenstein family.
Trevyn McDowell portrays Justine, a servant in the Frankenstein household who faces unjust accusations.
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