Al Pacino plays Officer Frank Serpico, an honest policeman who exposes corruption within the police force.
John Randolph portrays Sidney Green, a character associated with Frank Serpico.
Jack Kehoe plays Tom Keough, a fellow officer in the story.
Biff McGuire takes on the role of Captain McClain, a superior officer to Frank Serpico.
Barbara Eda-Young plays Laurie, a significant figure in Serpico's life.
Cornelia Sharpe portrays Leslie Lane, a character connected to the narrative.
Tony Roberts plays Bob Blair, a character involved in the unfolding events.
John Medici plays Pasquale, contributing to the storyline.
Allan Rich portrays D.A. Tauber, a character in the legal aspect of the story.
Norman Ornellas plays Rubello, adding to the film's portrayal of corruption.
Edward Grover plays Lombardo, another character in the police narrative.
Albert Henderson portrays Peluce, contributing to the film's depiction of police culture.
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