Amy Schumer stars as the protagonist Amy Townsend, a witty and independent writer who struggles with commitment in relationships.
Bill Hader plays Aaron Conners, a caring and understanding sports doctor who becomes romantically involved with Amy.
Brie Larson appears as Kim, Amy's sister who tries to guide her through the ups and downs of life and love.
Colin Quinn portrays Gordon Townsend, Amy and Kim's father, dealing with personal struggles and imparting wisdom to his daughters.
LeBron James showcases his acting skills as himself, a supportive friend of Aaron Conners who provides advice and humor.
John Cena takes on the role of Steven, a sensitive and humorous man who captures Amy's attention and heart.
Mike Birbiglia appears as Tom, a friend of Amy's who offers comic relief and moral support during her personal journey.
Vanessa Bayer plays Nikki, a colleague of Amy's who adds comedic moments and quirky charm to the story.
Ezra Miller portrays Donald, a unique and eccentric character who crosses paths with Amy during her adventures.
Tilda Swinton takes on the role of Dianna, Amy's no-nonsense boss who adds a touch of drama and chaos to her life.
Randall Park appears as Bryson, a friend of Aaron's who adds humor and light-hearted moments to the film.
Jon Glaser plays Schultz, a quirky and eccentric character who interacts with Amy and contributes comedic elements to the story.
Our free email delivers the daily top 10 TV shows and top 10 movies directly to your inbox. Stay ahead of the trends. Sign up below.